n.
- A wound or injury.
- A localized pathological change in a bodily organ or tissue.
- An infected or diseased patch of skin.
To cause a lesion to form on or in.
[Middle English lesioun, from Old French lesion, from Latin laesiō, laesiōn-, from laesus, past participle of laedere, to injure.]
The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2009. Published by Houghton Mifflin Company. All rights reserved.