Prilocaine is a topical anesthetic that is applied to the gingiva prior to the injection of the lidocaine. Prilocaine is not preferred over lidocaine in dentistry since they both have different jobs.

This mixture is used as an anaesthetic.

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Lidocaine is its own drug. it is of the caine family of drugs and often combined with benzocaine or prilocaine to produce a comound for anesthetic purposes.

Anna Taddio has written:

'Clinical pharmacology of lidocaine-prilocaine cream in infants'