The following is a list of the 50 largest pharmaceutical and biotech companies ranked by healthcare revenue as of 2008[update].[1] Some companies (eg, Johnson and Johnson and Procter & Gamble) have additional revenue not included here. The phrase Big Pharma is often used to refer to companies with revenue in excess of $3 billion,[citation needed] and/or R&D expenditure in excess of $500 million,[citation needed] and represents the first 30 or so companies in this list.[citation needed]
| Revenue Rank 2008 [2] | Company | Country | Total Revenues (USD millions) | Healthcare R&D 2008 (USD millions) | Net income/ (loss) 2008 (USD millions) | Employees 2008 |
|---|---|---|---|---|---|---|
| 1 | Pfizer[3] (with Wyeth[4]) | U.S. | 70,696 | 11,318 | 14,111 | 137,127 |
| 2 | Johnson & Johnson | U.S. | 63,747 | NA | 10,576 | 119,200 |
| 3 | Bayer [5] | Germany | 48,149 | 3,770 | 6,448 | 108,600 |
| 4 | Hoffmann–La Roche | Switzerland | 43,970 | NA | 8,135 | 78,604 |
| 5 | Novartis | Switzerland | 41,460 | NA | 11,946 | 98,200 |
| 6 | GlaxoSmithKline | United Kingdom | 40,424 | 6,373 | 10,432 | 103,483 |
| 7 | Sanofi-Aventis | France | 40,328 | NA | 7,204 | 99,495 |
| 8 | AstraZeneca | UK/Sweden | 31,601 | NA | 5,959 | 67,400 |
| 9 | Abbott Laboratories[6] | U.S. | 29,527 | 2,688 | 4,880 | 68,697 |
| 10 | Merck & Co. | U.S. | 23,850 | 4,678 | 7,808 | 74,372 |
| 11 | Bristol-Myers Squibb | U.S. | 19,977 | NA | 2,165 | 42,000 |
| 12 | Eli Lilly and Company | U.S. | 18,634 | NA9 | 2,953 | 40,600 |
| 13 | Boehringer Ingelheim | Germany | 16,959 | 1,977 | 2,163 | 43,000 |
| 14 | Takeda Pharmaceutical Co. | Japan | 15,697 | 1,620 | 2,870 | 15,000 |
| 15 | Amgen | U.S. | 14,771 | 3,366 | 3,166 | 48,000 |
| 16 | Genentech | U.S. | 13,400 | 15773 | 3,640 | 33,500 |
| 17 | Baxter International | U.S. | 12,300 | 614 | 1,397 | 38,428 |
| 18 | Teva Pharmaceutical Industries | Israel | 11,080 | 495 | 546 | 26,670 |
| 19 | Astellas Pharma | Japan | 10,701 | 1,435 | 1,122 | 23,613 |
| 20 | Daiichi Sankyo | Japan | 9,682 | 1,459 | 671 | 20,100 |
| 21 | Novo Nordisk | Denmark | 9,081 | 1,063 | 1,922 | 26,575 |
| 22 | Procter & Gamble | U.S. | 8,964 | n/a | 10,340 | 29,258 |
| 23 | Eisai | Japan | 5,583 | 926 | 604 | 14,993 |
| 24 | Merck KGaA | Germany | 5,175 | 772 | 1,258 | 13,900 |
| 25 | Alcon | U.S. | 4,897 | 512 | 1,348 | 13,500 |
| 26 | SINOPHARM | China | 4,700 | 498 | 1249 | 9700 |
| 27 | Akzo Nobel | Netherlands | 4,694 | 741 | 1,449 | 13,000 |
| 28 | UCB | Belgium | 4,426 | 1,024 | 492 | 12,741 |
| 29 | Nycomed | Switzerland | 4,264 | n/a | -105 | 10,533 |
| 30 | Forest Laboratories | U.S. | 3,442 | 941 | 454 | 9,649 |
| 31 | Solvay | Belgium | 3,268 | 533 | 1,026 | 9,000 |
| 32 | Genzyme | U.S. | 3,187 | 650 | -17 | 8,477 |
| 32 | Allergan | U.S. | 3,063 | 1,056 | -127 | 8,423 |
| 33 | Gilead Sciences | U.S. | 3,026 | 384 | -1,190 | 6,772 |
| 34 | CSL | Australia | 2,788 | 161 | 454 | 6,400 |
| 35 | Chugai Pharmaceutical Co. | Japan | 2,787 | 467 | 328 | 5,962 |
| 36 | Biogen Idec | U.S. | 2,683 | 718 | 218 | 5,907 |
| 37 | Bausch & Lomb | U.S. | 2,292 | 197 | 15 | 5,830 |
| 38 | Taiho Pharmaceutical Co. | Japan | 2,069 | 244 | 132 | 5,756 |
| 39 | King Pharmaceuticals | U.S. | 1,989 | 254 | 289 | 5,191 |
| 40 | Watson Pharmaceuticals | U.S. | 1,979 | 131 | -445 | 5,126 |
| 41 | Mitsubishi Pharma | Japan | 1,945 | 403 | 208 | 5,111 |
| 42 | Shire | UK | 1,797 | 387 | 278 | 4,958 |
| 43 | Cephalon | U.S. | 1,764 | 403 | 145 | 4,913 |
| 44 | Dainippon Sumitomo Pharma | Japan | 1,763 | 350 | 193 | 3,750 |
| 45 | Kyowa Hakko Kogyo | Japan | 1,698 | 268 | 108 | 2,895 |
| 46 | Shionogi | Japan | 1,640 | 320 | 159 | 2,868 |
| 47 | Mylan Laboratories | U.S. | 1,612 | 104 | 217 | 2,800 |
| 48 | H. Lundbeck | Denmark | 1,552 | 329 | 186 | 2,515 |
| 49 | MINT LIFE SCIENCES | India | 985 | 200 | 150 | 2,000 |
Contents |
Alphabetical listing
- It is limited to those companies notable enough to have articles in Wikipedia.
1-A
- 3M Pharmaceuticals is part of 3M, a diversified global technology company based in the U.S. that produces pharmaceuticals as part of its health care business
- Abbott Laboratories, a top-20 pharmaceutical company based in the U.S.[citation needed]
- Acambis a vaccine development company with offices in Cambridge, Massachusetts, U.S. and Cambridge, United Kingdom
- Alcon, a Swiss pharmaceutical company specialising in ophthalmology
- Alkaloid, based in Skopje, the Republic of Macedonia'
- Alkermes, a pharmaceutical company in Cambridge, Massachusetts,
- Allergan, headquartered in Irvine, California, U.S., is a global specialty company, producing [Ophthalmology|ophthalmic]] pharmaceuticals, dermatology products, and neurological products, with the most notable of the latter being BOTOX[citation needed]
- Almirall Prodesfarma, a Spanish multinational
- Alphapharm, an Australian generic pharmaceutical manufacturer and a wholly owned subsidiary of Merck KGaA
- Altana Pharma AG, formerly part of Altana AG. Since January 1, 2007, Altana Pharma is part of the Nycomed Group
- Amico Laboratories, a pharmaceutical company based in Bangladesh
- Amgen, a top-20 pharmaceutical company based in the U.S.[citation needed]
- Anthus Pharmaceuticals Pvt. Ltd, A pharmaceutical co. based at Chennai in India.
- Apotex, a generic pharmaceutical company based in Toronto, Canada
- Astellas Pharma, a Japanese company formed in 2005 through the merger of Fujisawa Pharmaceutical and Yamanouchi Pharmaceutical
- AstraZeneca, a top-20 pharmaceutical company[citation needed] based in the UK formed in 1999 through the merger of Astra AB and Zeneca Group PLC
- Axcan Pharma, a specialty pharmaceutical company based in Quebec, Canada
B-D
- Barr, a specialty pharmaceutical company based in the U.S.
- Bayer, a top-20 pharmaceutical company based in Germany,[citation needed] called Bayer Schering Pharma AG after the recent merger with the Schering Company, with headquarters moved from Leverkusen to Berlin.
- Beximco Pharmaceuticals Ltd, a pharmaceutical company based in Bangladesh
- Bial, a Portuguese pharmaceutical company
- Biogen Idec, a U.S.-based company formed in 2003 through the merger of Biogen and Idec Pharmaceuticals
- Biolex, a U.S.-based company
- BioPort, a U.S.-based vaccine manufacturer and a subsidiary of Emergent BioSolutions
- Biotecnol, a Portuguese company
- Biovail, the largest Canadian pharmaceutical company
- Biovitrum, a Swedish company
- Boehringer-Ingelheim, a top-20 pharmaceutical company based in Germany
- Bosch Pharmaceuticals Pvt Ltd. , Pakistan's leading pharmaceutical company specializing in Cephalosporins, Penicillins, Quinolones and Biotech products[citation needed]
- Bristol-Myers Squibb, a top-20 pharmaceutical company based in the U.S.[citation needed]
- Chemico Laboratories Ltd. is the largest company in Bangladesh
- Catalytica, a former U.S.-based company which merged with Synotex Company in 2000 to form DSM Catalytica Pharmaceuticals, now known as DSM Pharmaceuticals Products (DPP)
- Cephalon, A U.S based biopharmaceutical company that specialises in drugs for neural disorders and neurodegenerative diseases.
- Cipla, an Indian company best known as a manufacturer of anti-AIDS drugs[citation needed]
- Crucell, a Dutch biotechnology company specialising in vaccines
- Curix Pharma, an Indian pharmaceutical company[citation needed]
- Cypress Pharmaceutical, Inc., a specialty pharmaceutical company based in the United States.
- Daiichi Sankyo, a Japanese holding company established in 2005 for the management integration of Sankyo and Daiichi Pharmaceuticals
- Debiopharm, a Swiss pharmaceutical company
- Diabetology Ltd
- Dow Pharmaceutical Sciences, a U.S.-based company focused on topical therapeutics
- Douglas Pharmaceuticals A New Zealand based pharmaceuticals manufacturing company
- DSM Pharmaceuticals Products (DPP), a part of DSM, which is active worldwide in nutrition
E-L
- Élan Corporation, a pharmaceutical company based in Ireland.
- Eli Lilly and Company, a top-20 pharmaceutical company based in the U.S.[citation needed]
- Elorac, Inc., based in the US, is a specialty pharmaceutical company focused on advancing treatments in dermatology.
- Emergent BioSolutions, headquartered in Rockville, Maryland, develops and produces bioterrorism-related preventive and therapeutic products,[citation needed] such as for anthrax and botulism, and vaccines for typhoid, hepatitis B, and group B streptococcus
- Eskayef Bangladesh Limited, accredited by UK MHRA, a top-5 pharmaceutical company, pioneer pellet manufacturer & pharmaceutical product exporter of Bangladesh
- Ethypharm, a French company specialized in the development of drug delivery solutions for the pharmaceutical industry[citation needed]
- Etnabiotech, a subsidiary of Zydus Cadila, based on Catania, Sicily, Italy, aiming to develop vaccines based on virosomal technology or measles attenuated viruses against infectious diseases, such as malaria, HIV and HBV[citation needed]
- Evotec Ltd, a German company with research sites in the UK and California, working in the areas of sleeping disorders and obesity
- Ferozsons Laboratories, a Pakistani based company which is exclusively focused on Gastroenterology.
- Ferring Pharmaceuticals, a Switzerland based biopharmaceutical company which is focused on infertility, obstetrics, urology, gastroenterology, endocrinology and osteoarthritis.
- Fresenius Medical Care, a German based company with a branch in North America which is exclusively focused on Nephrology. Annual revenue of 10,4 billion in 2007.[citation needed]
- Galderma, a company with headquarters in Lausanne, Switzerland which is exclusively focused on Dermatology
- Genentech, a U.S.-based biopharmaceutical company taken over by Roche
- Genzyme, a U.S.-based company
- Getz Pharma, the largest pharmaceutical company in Pakistan[citation needed]
- Genix Pharma, the fast growing pharmaceutical company in Pakistan.[citation needed] Part of Genix Health Care Limited, UK and member of A&H Group of Companies, UK.
- Gishwi Healthcare, a Sri Lankan based healthcare importer
- Gilead Sciences, a US biopharmaceutical company
- GlaxoSmithKline, also known as GSK, Britain's largest pharmaceutical company[citation needed]
- Glenmark, India's leading Research based pharmaceutical Company[citation needed]
- GPC Biotech, a German biopharmaceutical company
- Grindex, the largest pharmaceutical company in the Baltic States.[citation needed]
- Guangxi Wonder Pharma, one of leading Corticosteroid manufacturers in China.[citation needed]
- Hetero Drugs, A vertically integrated indian generic pharmaceutical company.
- Hexal Australia, an Australian generic pharmaceutical manufacturer, part of the Hexal International Group
- Hexal International Group, a German generic pharmaceutical manufacturer
- Hikma, a multinational pharmaceutical company based in London, that manufactures branded and non-branded generic and in-licensed pharmaceutical products.
- Hoffmann-La Roche, or Roche, a top-20 pharmaceutical company based in Switzerland[citation needed]
- IMULAN BioTherapeutics, LLC, comparative medicine in immunobiology and infectious diseases
- iNova Pharmaceuticals (Australia) Pty Limited, formerly 3M Pharmaceuticals Pty Limited, a Sydney-based company that develops and markets over-the-counter and prescription medicines.
- Institute for OneWorld Health, a nonprofit U.S.-based pharmaceutical company focused on developing infectious disease drugs for developing countries[citation needed]
- Intercytex, a British healthcare company using its proprietary cell therapy technology to develop regenerative medicine products to restore skin and hair[citation needed]
- Isis Pharmaceuticals, a U.S.-based company focused on development of RNA-based therapeutics
- Janssen Pharmaceutica Products, a subsidiary of Johnson & Johnson
- Janssen-Cilag, a subsidiary of Johnson & Johnson
- Jelfa SA, a Polish generic pharmaceutical manufacturer
- JN-International Medical Corporation, a U.S.-based company focused on developing vaccines and diagnostics for infectious disease for developing countries
- Johnson & Johnson, a top-20 pharmaceutical company based in the U.S.[citation needed]
- King Pharmaceuticals, a U.S.-based company
- Knoll Pharmaceuticals, formerly the pharmaceutical division of BASF, acquired by Abbott in 2001
- Krka, d. d., a Slovenian generic pharmaceutical and cosmetics manufacturer
- Kurve Technology, Inc., a US company specialized in development of drug delivery solutions
- Lundbeck, a Danish company
M
- Mepha Ltd, Branded Generic Pharmaceutial Company based in, Swiss
- Macleods Pharmaceuticals, a generic pharmaceutical company based in Mumbai, India
- Mayne Pharma, an Australian pharmaceutical company acquired by Hospira in 2007
- Menarini
- Merck & Co., a top 10 pharmaceutical company, based in the US
- Macquin's International, Pharmaceutical Manufactures in Pakistan
- Merck KGaA, a top 30 pharmaceutical company, based in Germany
- Medopharm, an Indian pharmaceutical company
- Merix Pharmaceutical Corp. (Merix Health Care Products), a private company based in Barrington Hills, Illinois, US, manufactures Releev, an over the counter cold sore and shingles ointment
- Meyer Organics Private Limited, with HeadQuarters in Mumbai, Maharashtra, India, was founded in 1986 in collaboration with Omega-Meyer Ltd. of Jersey (British Isles)
- MG PRIME Pharmaceutical Inc, a pharmaceutical company based in the Philippines.
- MINT LIFE SCIENCES, a pharmaceutical company based in the India.
N
- NanoBio services, pharmaceutical generic manufacturer company in India(Mohali)
- Natco Pharma Limited, headquartered in Hyderabad, India, manufactures branded and generic dosage forms, bulk actives and intermediates for Indian and International markets
- CHINMAYA Pharmaceuticals
- Macquin's International Pharmaceutical Manufactures in Pakistan
- Nanomi, Drug Delivery Technology provider
- Napp Pharmaceuticals
- Neucon Pvt. Ltd., pharma of marketing sector, Head Office At Gulshan e Iqbal,Karachi
- Novartis
- Nectar Lifesciences an integrated pharmaceutical company in India that manufactures generic products
- Novo Nordisk, with the highest global market share of insulin & insulin delivery devices.[citation needed]
- Nucleics DNA sequencing reagents, services & software
- Nuclius Lifesciences India, manufactures branded and generic dosage forms, bulk actives and intermediates for Indian and International markets
- Nutra Pharma
O
- Ochoa Laboratories Limited
- Okasa Pharma Pvt Ltd, a leading pharmaceutical company of India[citation needed]
- Olainfarm, located in Olaine, Latvia, is the second largest pharmaceutical company[citation needed] in Latvia after Grindex
- Opsonin Pharma Limited, one of the largest drugs & medicine manufacturer and exporter[citation needed] in Bangladesh
- Ordain Health Care
- Ortho-McNeil Pharmaceutical
- Otsuka Pharmaceutical Co., based in Japan
- Orchid Pharmaa pharmaceutical company based in India
- Onox Interworld Ent., one of the leading drug distributor based in The Philippines.
- OZ Biosciences S.A.S., Creates, develops and produces reagent based on molecular delivery system.
P
- Pak Fah Yeow International Limited, known for the Hoe Hin brand [7]
- Pfizer, world largest pharmaceuticals company
- Pharmacosmos, a pharmaceutical company based in Denmark
- Pharmed Medicare, among the top five fastest growing companies[citation needed]
- PharmEvo Pvt Ltd, a leading pharmaceutical company of Pakistan[citation needed]
- Pharma Nord, private company, Denmark
- Pierre Fabre Group
- Pliva
- Popular Pharmaceuticals Ltd, the pioneer manufacturer of generic Biotech formulations (Human Insulin) in Bangladesh[citation needed]
- Procter & Gamble
- PRO.MED.CZ Praha a.s., Czech Republic
- Purdue Pharma, private company, maker of Oxcycontin
- Pharmapick, Fastest growing marketing support company, makers of Visual Aids, Literature s, Patient Education Programmes
R
- Ranbaxy, Generic arm of Daichi Sankyo
- Rhys Health care Pvt Ltd
- Renovo is a biopharmaceutical company based in Manchester, UK
- Respa Pharmaceuticals, Inc, a US based solid dosage manufacturer/distributor
- Roche research-focused healthcare with combined strengths in pharmaceuticals and diagnostics
S
- Shuzhong Pharmacy Co.,Ltd., Top 5 pharmaceutical company in China
- Sinoway Pharmaceuticals Manufacturer one of the best pharmaceutical companies from China[citation needed]
- Sara Pharmaceuticals, a growing pharmaceutical company from India[citation needed]
- Searle Pakistan Limited (SPL), one of the leading pharmaceutical companies in Pakistan[citation needed]
- Sanofi-Aventis, a global top-20 pharmaceutical company based in France[citation needed]
- Sanquin Pharmaceutical Services, a Dutch company
- Sepracor, a growing pharmaceutical company[citation needed] whose products include Lunesta and Xopenex
- Servier Laboratories
- Shire Pharmaceuticals Group, a British company
- Sigma Pharmaceuticals Limited, an Australian company
- Siza International Limited, a Pakistani company
- Solvay Group
- [Square Pharmaceuticals Limited], largest pharmaceutical company in Bangladesh
- Stratpharma AG, a Swiss pharmaceutical company, focused on dermatology
- Strides Arcolab Limited, one of the world leaders in softgel capsule
- Sun Pharmaceuticals, headquartered in Mumbai, India, make pharmaceuticals and speciality Active Pharmaceutical Ingredients (API) for international markets and for India
- Swiss Health.,
- SwissPharmatech Co., a global Pharmaceutical Firm focusing on Cardiovascular and Antidiabetic Drugs based in the Philippines.
T
- Takeda, a top-20 pharmaceutical company based in Japan[citation needed]
- TAP Pharmaceutical Products, Inc, a joint-venture of Abbott and Takeda, created without discovery or manufacturing capabilities
- Temmler, pharmaceutical contract manufacturer with production sites in Germany, Ireland, Italy and Switzerland an independent manufacturer of branded generics
- Teva Pharmaceutical Industries, a global (top-20) manufacturer of mainly generic pharmaceuticals, based in Israel.[citation needed]
- Torrent Pharmaceuticals, a global manufacturer of mainly generic pharmaceuticals, based in India.[citation needed]
- T&G Medicare, a manufacturer of mainly generic pharmaceuticals, based in India.www.tandgmedicare.com
U-Z
- UCB, a Belgian biopharmaceutical company
- Valeant, formerly ICN Pharmaceuticals, a U.S.-based company
- Vertex Pharmaceuticals, a U.S.-based company
- Vion Pharmaceuticals, Inc., a U.S.-based company
- ViroPharma, a U.S.-based company
- Wings Pharmaceuticals Pvt. Ltd. , an India company with major national top brand genrics . A 20.8 million dollar company
- XL Laboratories Pvt. Ltd. , an India based manufacturing and exporting company having presence in more than 22 nations
- Zeltia, a Spanish holding company whose Biotechnological Sector subsidiaries includes PharmaMar, Genomica, S.A.U., Neuropharma and Sylentis S.A.U..[8]
- Zentiva, a Czech company
See also
- International Federation of Pharmaceutical Manufacturers and Associations
- European Federation of Pharmaceutical Industries and Associations (EFPIA)
- Pharmaceutical Research and Manufacturers of America (PhRMA)
- List of pharmaceutical manufacturers in the UK
- List of biotechnology companies
- EuropaBio, the European Association for Bioindustries
References
- ^ "Global 500" (web). 2008. http://money.cnn.com/magazines/fortune/global500/2008/index.html. Retrieved 2009-07-27.
- ^ "Global 500" (web). 2008. http://money.cnn.com/magazines/fortune/global500/2008/index.html. Retrieved 2009-07-27.
- ^ "Pfizer Annual Report" (PDF). 2008. http://media.pfizer.com/files/annualreport/2008/annual/review2008.pdf. Retrieved 2009-07-24.
- ^ "Wyeth Annual Report" (PDF). 2008. http://phx.corporate-ir.net/External.File?item=UGFyZW50SUQ9ODM4NnxDaGlsZElEPS0xfFR5cGU9Mw==&t=1. Retrieved 2009-07-24.
- ^ "Kennzahlen Bayer Konzern" (web). 2008. http://www.geschaeftsbericht2008.bayer.de/de/Kennzahlen.aspx. Retrieved 2009-07-27.
- ^ "Abbott Annual Report" (PDF). 2008. http://www.abbott.com/static/content/microsite/annual_report/2008/support_files/ABT_AR_08_onlinefull.pdf. Retrieved 2009-07-24.
- ^ http://www.baihuayou.com/e/default_home.asp
- ^ Regarding PharmaMar and Neuropharma: O'Neill, Michael F.; McGettigan, Gerard (15 August 2005), Table 2: Service and products for a selection of Spanish biotechnology companies, "Spanish biotechnology: anyone for PYMEs?", Drug Discovery Today, News and Comment 10 (16): 1080, doi:, ISSN 1359-6446
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