Yes, Demerol can be used with a loop diuretic

A loop diuretic affects the loops of Henle which regulate the uptake of sodium. The diuretic signal the kidney not to absorb calcium, potassium and magnesium and sodium The side effects are muscle weakness , cramps and palpitations.

Loop diuretics have the quickest onset of action. They are called loop diuretics because they act in the loop of henle in the kidneys. The main loop diuretics are: Furosemide, Bumetanide and Torasemide

Only indirectly. If too much of a loop diuretic (e.g. furosemide) is taken, and the individual becomes severely dehydrated, as a result, then it is possible for a metabolic encephalopathy to ensue, thus causing confusion, mumbled or slurred speech, and more.

jamela Mae alcubilla