Dictionary:
lym·pho·blast (lĭm'fə-blăst') ![]() |
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| Veterinary Dictionary: lymphoblast |
The immature, nucleolated precursor of the mature lymphocyte. Called also large lymphocyte.
| Wikipedia: Lymphoblast |
Lymphoblasts are immature cells which typically differentiate to form mature lymphocytes. Normally lymphoblasts are found in the bone marrow, but in acute lymphoblastic leukemia (ALL), lymphoblasts proliferate uncontrollably and are found in large numbers in the peripheral blood.
Although commonly lymphoblast refers to a precursor cell in the maturation of leukocytes, the usage of this term is sometimes inconsistent. The Chronic Lymphocytic Leukemia Research Consortium defines a lymphoblast as "A lymphocyte that has become larger after being stimulated by an antigen. Lymphoblasts look like immature lymphocytes, and were once thought to be precursor cells."[1]. Commonly, when speaking about leukemia, "blast" is used as an abbreviation for lymphoblasts.
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They are 2.5 micrometres in size.
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Copyrights:
![]() | Dictionary. The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2009. Published by Houghton Mifflin Company. All rights reserved. Read more | |
![]() | Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved. Read more | |
![]() | Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "Lymphoblast". Read more |