Prevention of lymphogranuloma venereum has four important aspects: Avoidance of casual sexual contacts, particularly with prostitutes, in countries with high rates of the disease. Observance of proper safeguards by health professionals.

Lymphogranuloma venereum (LGV) is a sexually transmitted systemic disease (STD) caused by a parasitic organism closely related to certain types of bacteria. It affects the lymph nodes and rectal area, as well as the genitals.

The most common bacterial STDs in the US are gonorrhea, chlamydia, and syphilis. Other bacterial STDs include mycoiplasma, lymphogranuloma venereum and chancroid.

There are several blood tests that can be used to confirm the diagnosis of LGV. The most commonly used are the complement fixation (CF) test and the microimmunofluorescence (micro-IF) tests.

Depending on context, LGV may stand for "Ligne à grande vitesse", or high speed train (HST) in English; or it may stand for lymphogranuloma venereum, a sexually transmitted disease.