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lysogeny

 
Dictionary: ly·sog·e·ny   (lī-sŏj'ə-nē) pronunciation
n.
The fusion of the nucleic acid of a bacteriophage with that of a host bacterium so that the potential exists for the newly integrated genetic material to be transmitted to daughter cells at each subsequent cell division.


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Type of life cycle that takes place in a bacteriophage after it infects certain types of bacteria. The bacteriophage's genome (entire collection of genes) enters the chromosome of the host bacterium and replicates together with it. No offspring viruses are produced; instead, the infecting virus lies dormant within the host's chromosome until the host is exposed to certain stimuli, such as ultraviolet light. At that point, the virus genome is removed from the host chromosome and begins to multiply, forming new viruses. Finally, the bacterial host is destroyed (lysed), releasing virus particles into the environment to infect new bacterial cells.

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Sci-Tech Encyclopedia: Lysogeny
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Almost all strains of bacteria are lysogenic; that is, they have the capacity on rare occasions to lyse with the liberation of particles of bacteriophage (see illustration). Such particles can be detected by their ability to form plaques (colonies of bacteriophage) on lawns of sensitive (indicator) bacteria. The genetic determinant of the capacity of lysogenic bacteria to produce bacteriophage is a repressed phage genome (provirus) which exists in the bacterium in one of two states: (1) integrated into the bacterial chromosome (most cases), or (2) occupying some extra-chromosomal location (rare cases).

Life cycles of phage and bacterial host. (<i>After E. Jawetz, J. L. Melnick, and E. A.Adelberg, Review of Medical Microbiology, 2d ed., Lange, 1956</i>)
Life cycles of phage and bacterial host. (After E. Jawetz, J. L. Melnick, and E. A.Adelberg, Review of Medical Microbiology, 2d ed., Lange, 1956)

Bacteriophages which have the potential to exist as provirus are called temperate phages. When the provirus is integrated into the bacterial genome, it is called prophage. When the germinal substance (deoxyribonucleic acid or deoxyribonucleoprotein) of certain temperate phages enters a sensitive bacterium, the outcome may be death (lysis) for the bacterium as a result of phage multiplication, or it may result in the integration of the phage nucleic acid into the host genome (as a prophage), with the formation of a stable lysogenic bacterium. The lysogenic strain is designated by the name of the sensitive strain followed, in parentheses, by the strain of lysogenizing phage, for example, Escherichia coli (λ). Such a bacterium differs from its nonlysogenic ancestor in one very special way: It is immune to lysis by phage homologous to its carried prophage. See also Bacteriophage.


Medical Dictionary: ly·sog·e·ny
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(lī-sŏj'ə-nē)
n.

The fusion of the nucleic acid of a bacteriophage with that of a host bacterium so that the potential exists for the newly integrated genetic material to be transmitted to daughter cells at each subsequent cell division.

WordNet: lysogeny
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Note: click on a word meaning below to see its connections and related words.

The noun has one meaning:

Meaning #1: the condition of a host bacterium that has incorporated a phage into its own genetic material
  Synonym: lysogenicity


 
 
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lysogen
lysogenic
Coliphage (virology)

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Dictionary. The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2009. Published by Houghton Mifflin Company. All rights reserved.  Read more
Britannica Concise Encyclopedia. Britannica Concise Encyclopedia. © 2006 Encyclopædia Britannica, Inc. All rights reserved.  Read more
Sci-Tech Encyclopedia. McGraw-Hill Encyclopedia of Science and Technology. Copyright © 2005 by The McGraw-Hill Companies, Inc. All rights reserved.  Read more
Medical Dictionary. The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company Read more
WordNet. WordNet 1.7.1 Copyright © 2001 by Princeton University. All rights reserved.  Read more