An avermectin is any of a class of macrocyclic lactones,
produced by Streptomyces bacteria, and used to kill parasites.
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by adding the dilute acid metal can be removed from macrocyclic
complexes.in this way macrocycles will be free
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Environmental factors,ionisation potential,electronegativity,
nature of ligands ,macrocyclic effects ,steric effects and role of
PH.
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According to
Tapani Tuomi, Lauri Saarinen and Kari Reijula (1998): Detection
of polar and macrocyclic trichothecene mycotoxins from indoor
environments. Analyst, 123, 1835-1841