Share on Facebook Share on Twitter Email
Answers.com

Mallory body

 
Sci-Tech Dictionary: Mallory bodies
Home > Library > Science > Sci-Tech Dictionary
(′mal·ə·rē ′bäd·ēz)

(pathology) Oval acidophilic hyalin inclusion bodies seen in the cytoplasm of hepatic cells in Laennec's cirrhosis. Also known as alcoholic hyaline.

Search unanswered questions...

Enter a question here...
Search: All sources Community Q&A Reference topics

Medical Dictionary: Mal·lo·ry body
Top
Home > Library > Health > Medical Dictionary
(măl'ə-rē)
n.

A poorly defined accumulation of eosinophilic material in the cytoplasm of damaged liver cells in certain forms of cirrhosis.

Wikipedia: Mallory body
Top
Home > Library > Miscellaneous > Wikipedia
Micrograph showing a Mallory body with the characteristic twisted-rope appearance (centre of image - within a ballooning hepatocyte). H&E stain.

In histopathology, a Mallory body, also known as alcoholic hyaline, Mallory-Denk body, and Mallory's hyaline, is an inclusion found in the cytoplasm of liver cells.[1]

They are classically found in the livers of people suffering from alcoholic liver disease and were once thought to be specific for that.

They are most common in alcoholic hepatitis (prevalence of 65%) and alcoholic cirrhosis (prevalence of 51%).[2]

They are a recognized feature of Wilson's disease (25%), primary biliary cirrhosis (24%), non-alcoholic cirrhosis (24%), hepatocellular carcinoma (23%) and morbid obesity (8%), among other conditions.[2]

Contents

Appearance

They are highly eosinophilic and thus appear pink on H&E stain. The bodies themselves are made up of intermediate keratin filament proteins that have been ubiquinated, or bound by other proteins such as heat shock proteins, or p62.

Eponym

It is named for Frank Burr Mallory.[3]

See also

Additional images

Micrograph showing a Mallory body. Original magnification 400X. H&E stain.

Micrograph showing a Mallory body. Original magnification 200X. H&E stain.

Liver micrograph showing abundant Mallory bodies, as seen in alcohol abuse.

References

  1. ^ "Cell Injury". http://library.med.utah.edu/WebPath/CINJHTML/CINJ033.html. 
  2. ^ a b Jensen, K; Gluud, C (Oct 1994). "The Mallory body: morphological, clinical and experimental studies (Part 1 of a literature survey).". Hepatology 20 (4 Pt 1): 1061-77. PMID 7927209. 
  3. ^ synd/2192 at Who Named It?
Stub icon This article related to pathology is a stub. You can help Wikipedia by expanding it.
v • d • e
Eponymous medical signs for digestive system and abdomen
Digestive system
Abdominopelvic
Other
Abdominal · general
digestive system navs: anat of tract,glands,perit,diaphragm/physio/dev, noncongen/congen/congen of d+w/neoplasia, symptoms+signs/eponymous, proc

This entry is from Wikipedia, the leading user-contributed encyclopedia. It may not have been reviewed by professional editors (see full disclaimer)

 
 
Learn More
Blumberg sign
Aaron's sign
Dance's sign

What is mallory in spanish? Read answer...
Who is mallory soccadoto? Read answer...
What does Mallori mean? Read answer...

Help us answer these
Who is mallory anderson?
What is Italian for 'Mallory'?
Is there a Mallory Payne?

Post a question - any question - to the WikiAnswers community:

 

Copyrights:

Sci-Tech Dictionary. McGraw-Hill Dictionary of Scientific and Technical Terms. Copyright © 2003, 1994, 1989, 1984, 1978, 1976, 1974 by McGraw-Hill Companies, Inc. All rights reserved.  Read more
Medical Dictionary. The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company.  Read more
Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "Mallory body".  Read more