Manganese is required by the body for normal growth and health. It helps your body break down fats, carbohydrates, and proteins. In the human body, manganese functions as an …enzyme activator and as a component of metalloenzymes (an enzyme that contains a metal ion in its structure). Manganese can: .
Activate enzymes : Manganese activates the enzymes that help your body use several key nutrients including biotin, thiamine, vitamin C, and choline. It is a catalyst in the synthesis of fatty acids and cholesterol, it facilitates protein and carbohydrate metabolism, and it may also help your body produce sex hormones and maintain reproductive health. In addition, manganese activates the enzymes known as glycolsyltranserferases and xylosyltransferases, which are important in forming bone. Manganese may also be involved in the production of the thyroid hormone known as thyroxine and in maintaining the health of nerve tissue. .
Form metalloenzymes : Manganese has additional functions as a constituent of the following metalloenzymes (enzymes that contain a metal ion in their structure): .
Arginase, the enzyme in your liver responsible for creating urea, a component of urine .
Glutamine synthetase, an enzyme involved in the synthesis of glutamine .
Phosphoenolpyruvate decarboxylase, an enzyme that helps metabolize blood sugar .
Manganese-dependent superoxide dismutase, an enzyme with antioxidant activity that protects your tissues from the damaging effects of free radicals.This enzyme is found exclusively inside your mitochondria (oxygen-based energy factories inside most of your cells). ( Full Answer )