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Megakaryocyte

Q: What are the ancestral cell of platelets?

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Megakaryocyte

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megakaryocyte

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The precursor cell to blood platelets are megakaryocyte precursor (MkP) cells in the bone marrow.

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The megakaryoblast undergoes endomitoses (the nucleus becomes polyploid and the cell does not divide) and ultimately develops into megakaryocyte.

The successive stages are Megakaryoblast -> Promegakaryocyte -> Megakaryocyte

Megakaryocyte produces thrombocytes, that is fragments of megakraryocyte' cytoplasm.

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This is known as a megakaryocyte.

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