CADASIL is characterized by a series of strokes, which is thought to be triggered by genetically determined deficiencies of small cerebral arteries.

In general, a brain that weighs more than 1600 grams (about 3.5 pounds) is considered megalencephalic. The heaviest brain on record weighed 2850 grams (about 6.3 pounds). Macrocephaly, a related condition, refers to an abnormally large head

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The term subcortical refers to structures or processes that lie beneath the cerebral cortex in the brain. These subcortical structures are involved in functions such as regulating emotions, motor control, and processing sensory information.

The cysts that appear during the regular activity of the ovaries are called functional cysts.