When the mesial buccal cusp of the maxillary first molar is
distal to the mesial buccal cusp of the mandibular first molar.
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Mesial refers to the side or surface of a structure that is closer to the midline of the body or to a specific reference point. In dentistry, it is used to describe a tooth surface that is closer to the front of the mouth.
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The concavity that forms on the mesial aspect of maxillary first
premolars is called the cuspid groove. It is the result of the
first premolar having both a buccal and palatal root. The groove
functions as an alignment guide for the maxillary cuspid as it
descends into the mouth.