metathesis

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(mĭ-tăth'ĭ-sĭs) pronunciation
n., pl., -ses (-sēz').
  1. Linguistics. Transposition within a word of letters, sounds, or syllables, as in the change from Old English brid to modern English bird or in the confusion of modren for modern.
  2. Chemistry. Double decomposition.

[Late Latin, from Greek, from metatithenai, to transpose : meta-, meta- + tithenai, to place.]

metathetic met'a·thet'ic (mĕt'ə-thĕt'ĭk) or met'a·thet'i·cal adj.
metathetically met'a·thet'i·cal·ly adv.


pronounced with the stress on the second syllable, is a term for the transposition of sounds or letters in a word, sometimes as a feature of a word's development (e.g hasp from Old English hæpse) and at other times as an erroneous process (e.g. anenome for anemone).

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A type of reaction in which radicals are exchanged. In inorganic chemistry, it is also called double decomposition. A simple example is

KCL+AgNO3 → KNO3+AgCl.
Metathesis of alkenes is an important type of reaction in synthetic organic chemistry. It involves exchange of groups. For example
RHC=CH2+RHC=CH2 → RHC=CHR+H2C=CH2.
Reactions of this type are catalysed by metal alkylides (containing an M=CR2 grouping) and the intermediate is a four-membered ring containing the metal ion. The catalysts most often used are the Schrock catalysts based on molybdenum and the Grubbs catalysts based on ruthenium. The American chemists Richard Schrock and Robert Grubbs shared the Nobel prize for chemistry in 2005 for work in this field.



1. artificial transfer of a morbid process.
2. a chemical reaction in which an element or radical in one compound exchanges places with another element or radical in another compound.

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Random House Word Menu by Stephen Glazier
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Metathesis (from the Greek μετάθεσις "transposition") may refer to:

  • Metathesis (linguistics), in phonology, a sound change that alters the order of phonemes in a word
    • Quantitative metathesis, a situation in which two vowel sounds follow directly one after the other and a transposition of vowel length takes place
  • Metathesis reaction, in chemistry, a bimolecular process involving the exchange of bonds between the two reacting chemical species
    • Olefin metathesis, an organic reaction which involves redistribution of olefinic (alkene) bonds
    • Alkane metathesis, a chemical reaction in which alkanes are rearranged to give longer or shorter alkane products
    • Alkyne metathesis, an organic reaction involving the redistribution of alkyne chemical bonds

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driving force (chemistry)
Robert Howard Grubbs (American chemist)