Muscle atrophy refers to the wasting or loss of muscle tissue resulting from disease or lack of use.

Disuse of a muscle causes atrophy, which is a shrinking of muscle fibers leading to weakness. With use, the atrophy can be reversed.

atrophy is a decrease in muscle mass. Hypertrophy is muscle growth.

diuse atrophy (muscle loss or weakness from lack of use)

Muscle atrophy can affect any muscle within the body. Atrophy is a wasting or decrease in size of a body organ, tissue, or part owing to disease, injury, or lack of use. Any muscle is subject to atrophy from either lack of use or disease. This is especially true after injury or extended bedrest. To answer your question there are no two prominent muscles that are exclusively affected in muscle atrophy.