N-Acetylgalactosamine
Oxford Dictionary of Biochemistry:
Top
N-acetylgalactosamine
symbol: d-GalpNAc; abbr.: NAGA; the d isomer, 2-acetamido-2-deoxy-d-galactopyranose, is a common structural unit of oligosaccharides, such as the blood-group substances and O-linked glycoproteins, in which the sugar is in glycosidic linkage to a protein or serine residue, or, in the case of the blood-group substances, to a lipid hydroxyl group. The reactant in synthetic reactions is UDP-N-acetylgalactosamine, which is formed by epimerization of N-acetylglucosamine.
| N-acetylcysteine, N-acetylaspartate, N-acetyl transferase | |
| N-acetylgalactosamine-4-sulfatase, N-acetylgalactosamine-6-sulfatase, N-acetylgalactosaminidase |
Saunders Veterinary Dictionary:
Top
N-acetylgalactosamine
One of the repeating disaccharide units in glycosaminoglycans.
Wikipedia on Answers.com:
Top
N-Acetylgalactosamine
| N-Acetylgalactosamine | |
|---|---|
 |
|
|
2-(Acetylamino)-2-deoxy-D-galactose |
|
|
Other names
GalNAc; 2-Acetamido-2-deoxy-D-galactose; N-Acetylchondrosamine; 2-Acetamido-2-deoxy-D-galactopyranose; N-Acetyl-D-galactosamine |
|
| Identifiers | |
| CAS number | 31022-50-1  |
| PubChem | 84265 |
| ChemSpider | 76020  |
| ChEBI | CHEBI:40356 |
| Jmol-3D images | Image 1 |
|
|
|
|
| Properties | |
| Molecular formula | C8H15NO6 |
| Molar mass | 221.21 g/mol |
| Melting point |
172–173 °C |
| Hazards | |
| S-phrases | S24/25 |
| Related compounds | |
| Related monosaccharides | N-Acetylglucosamine Galactosamine Galactose |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
|
| Infobox references | |
N-Acetylgalactosamine (GalNAc), is an amino sugar derivative of galactose.
Function
In humans it is the terminal carbohydrate forming the antigen of blood group A.[1]
It is typically the first monosaccharide that connects serine or threonine in particular forms of protein O-glycosylation.
N-Acetylgalactosamine is necessary for intercellular communication, and is concentrated in sensory nerve structures of both humans and animals.
See also
References
- ^ Donald M. Marcus, Elvin A. Kabat, Gerald Schiffman (1964). "Immunochemical Studies on Blood Groups. XXXI. Destruction of Blood Group A Activity by an Enzyme from Clostridium tertium Which Deacetylates N-Acetylgalactosamine in Intact Blood Group Substances". Biochemistry 3: 437–443. doi:10.1021/bi00891a023. http://pubs.acs.org/doi/abs/10.1021/bi00891a023.
This entry is from Wikipedia, the leading user-contributed encyclopedia. It may not have been reviewed by professional editors (see full disclaimer)
Post a question - any question - to the WikiAnswers community:
Copyrights:
Oxford Dictionary of Biochemistry
Oxford University Press. Oxford Dictionary of Biochemistry and Molecular Biology © 1997, 2000, 2006 All rights reserved.
Read more
Saunders Veterinary Dictionary
Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved.
Read more
