The Nasolacrimal duct allows entry into the systemic
circulation. If a medication will cause systemic effects, you will
want to block the Nasolacrimal duct with gentle pressure.
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The nasolacrimal duct carries excess tears into the nasal
cavity. This is why you get a runny nose when you cry.
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In animals, the nasolacrimal duct is a tear duct. This duct
carries tears from the lacrimal sac to the nasal cavity.