A disease or abnormality of the kidney.
nephropathic neph'ro·path'ic (nĕf'rə-păth'ĭk) adj.
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Results for nephropathy
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Veterinary Dictionary:
nephropathy
Any disease of the kidneys.
- analgesic n. — see analgesic nephropathy.
- baby chick n. — see visceral gout.
- familial n. — different types of renal disease have been recorded as occurring on a familial basis in Finnish-Landrace sheep and several breeds of dogs, including Lhasa apsos, Shih tzus, Samoyeds, Bull terriers, Norwegian elkhounds, Cocker spaniels and Basenjis.
- hypercalcemic n. — see nephrocalcinosis.
- juvenile n. — suspected of being familial in many dog breeds especially Malamute, Miniature schnauzer, Keeshond, German shepherd; characterized by renal failure in immature or young adult dogs. The pathogenesis is poorly understood, hence the retention of the title nephropathy.
- mycotoxic n. — caused by mycotoxins, such as ochratoxin and citrinin, produced by Penicillium and Aspergillus spp.
- pigment n. — see hemoglobinuric nephrosis.
- reflux n. — pyelonephritis in which the renal scarring results from vesicoureteric reflux, with radiological appearance of intrarenal reflux.
Wikipedia:
nephropathy
Nephropathy refers to damage to or disease of the kidney. An older term for this is nephrosis.
Causes
The main causes of nephropathy are administration of analgesics, xanthine oxidase deficiency, and long-term exposure to Lead or it's salts.
Analgesics
One cause of nephropathy is the long term usage of analgesics. The pain medicines which can cause kidney problems include aspirin, acetaminophen, and nonsteroidal anti-inflammatory drugs, or NSAIDs. This form of nephropathy is "chronic analgesic nephritis," a chronic inflammatory change characterized by loss and atrophy of tubules and interstitial fibrosis and inflammation (BRS Pathology, 2nd edition).
Specifically, long term use of the analgesic phenacetin has been linked to renal papillary necrosis (necrotizing papillitis).
Xanthine oxidase deficiency
A second possible cause of nephropathy is due to decreased function of xanthine oxidase in the purine degradation pathway. Xanthine oxidase will degrade hypoxanthine to xanthine and then to uric acid. Xanthine is not very soluble in water; therefore, an increase in xanthine forms crystals (which can lead to kidney stones) and result in damage of the kidney. Drugs like allopurinol that are used to inhibit xanthine oxidase can therefore cause possible nephropathy.
See also
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Copyrights:
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 | Dictionary. The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2007. Published by Houghton Mifflin Company. All rights reserved. Read more |
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| Dental Dictionary. Mosby's Dental Dictionary. Copyright © 2004 by Elsevier, Inc. All rights reserved. Read more |
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| Veterinary Dictionary. The Veterinary Dictionary. Copyright © 2007 by Elsevier. All rights reserved. Read more |
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| Wikipedia. This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Nephropathy". Read more |
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