Many people were hated and considered heretics by many throughout the centuries:The Circumcisers (1st Century)
Gnosticism (1st and 2nd Centuries)
Montanism (Late 2nd Century)
Sabellianism (Early 3rd Century)
Arianism (4th Century)
Pelagianism (5th Century)
Semi-Pelagianism (5th Century)
Nestorianism (5th Century)
Monophysitism (5th Century)
Iconoclasm (7th and 8th Centuries)
Catharism (11th Century)
Protestantism (16th Century)
Jansenism (17th Century)
The most enduring heresy to date has been the Protestant heresy, although several other lasted quite a long time, and truly Protestantism has elements of most of the earlier heresies in it.