The nociceptor transmits its signal to nerve cells within the
spinal cord, which conveys the pain message to the thalamus, a
specific region in the brain.
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nociceptors
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nociceptor
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Nerve cell endings, or receptors, are at the front end of pain
sensation. A stimulus at this part of the nociceptor unleashes a
cascade of neurotransmitters (chemicals that transmit information
within the nervous system) in the spine.