Treatment of the symptoms of opsoclonus myoclonus include clonzaepam or valproate. These may decrease the severity of both the opsoclonus and the myoclonus.

Diagnosis is primarily arrived at through identification of concurrent opsoclonus and myoclonus.

In children, the most common type of tumor that precipitates opsoclonus myoclonus is called neuroblastoma.

Most children who develop opsoclonus myoclonus are under the age of two when they are diagnosed.

Rarely, opsoclonus myoclonus can occur after the use of certain medications such as intravenous phenytoin or diazepam , or subsequent to an overdose of the antidepressant amitriptyline