adj.
Resembling bone.
n.
The bone matrix, especially before calcification.
osteoid
Dictionary:
os·te·oid (ŏs'tē-oid')  |
| 5min Related Video: osteoid |
| Dental Dictionary: osteoid |
(os′tē oid)
n
n
The muco-polysaccharide-protein complex laid down by the osteoblasts. It is later calcified, with inclusion of osteoblasts as osteocytes within lacunae, into bone.
| Medical Dictionary: os·te·oid |
| Veterinary Dictionary: osteoid |
1. resembling bone.
2. the organic matrix of bone; young bone that has not undergone calcification.
| Wikipedia: Osteoid |
In histology, osteoid is the unmineralized, organic portion of the bone matrix that forms prior to the maturation of bone tissue. Osteoblasts begin the process of forming bone tissue by secreting the osteoid as several specific proteins. When the osteoid becomes mineralized, it and the adjacent bone cells have developed into new bone tissue.
Osteoid makes up about fifty percent of bone volume and twenty-five percent of bone weight. It is composed of fibers and ground substance. The predominant fiber-type is Type I collagen. The ground substance is mostly made up of chondroitin sulfate and osteocalcin.
When there is insufficient mineral or osteoblast dysfunction, the osteoid does not mineralize properly, and it accumulates. This process is called osteomalacia. Osteomalacia, when present in children, is defined as rickets.
References
- Netter, Frank H. (1987), Musculoskeletal system: anatomy, physiology, and metabolic disorders. Summit, New Jersey: Ciba-Geigy Corporation
External links
- Histology at OU 69_03 - "Bone, femur"
- Dr. Susan Ott's website on osteomalacia
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 | Dictionary. The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2009. Published by Houghton Mifflin Company. All rights reserved. Read more |
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| Dental Dictionary. Mosby's Dental Dictionary. Copyright © 2004 by Elsevier, Inc. All rights reserved. Read more |
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| Medical Dictionary. The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Read more |
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| Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved. Read more |
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| Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "Osteoid". Read more |
