Over-the-counter, also known as OTC, may refer to:
- Over-the-counter drug -- medicine that may be sold without a prescription and without a visit to a prescriber (ie. doctor, dentist, vet), in contrast to prescription drugs. In some countries (eg. Australia) consultation is required with trained pharmacy staff or a pharmacist to ensure safe and efficacious use of medications. Over-the-counter medications are not appropriate for all people.
- Over-the-counter (finance), financial instruments, such as stocks, exchanged directly between two parties.
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