From MedicineNet.com:
" Paget's disease is a chronic bone condition characterized by
disorder of the normal bone remodeling process. Normal bone has a
synchronized relationship of mechanisms that act to lay down new
bone and take up old bone. This relationship (referred to as
remodeling) is essential for maintaining the normal calcium levels
in our blood. In bone affected by Paget's disease, the bone
remodeling is disturbed and not synchronized. As a result, the bone
that is formed is abnormal, enlarged, not as dense, brittle, and
prone to breakage (fracture).
Paget's disease affects older bone of adults. It's estimated
that 1% of adults in the U.S. have Paget's disease. There is an
extremely rare form of Paget's disease in children, referred to as
juvenile Paget's disease. Paget's disease is also known as osteitis
deformans."
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