pancreatic juice

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The alkaline digestive juice produced by the pancreas and secreted into the duodenum. It contains the inactive precursors of a number of protein digestive enzymes. Trypsinogen is activated to trypsin by enteropeptidase in the intestinal lumen; in turn, trypsin activates the other enzyme precursors: chymotrypsinogen to chymotrypsin, pro-elastase to elastase, procarboxypeptidase to carboxypeptidase. Also contains lipase, amylase, and nucleases.

• Endocrine System and Glands - pancreatic juice: digestive juice secreted by pancreas and passed to duodenum

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Pancreatic juice is a liquid secreted by the pancreas, which contains a variety of enzymes, including trypsinogen, chymotrypsinogen, elastase, carboxypeptidase, pancreatic lipase, and amylase.

Pancreatic juice is alkaline in nature due to the high concentration of bicarbonate ions. This is useful in neutralizing the acidic gastric acid, allowing for effective enzymic action.

Pancreatic juice secretion is regulated by the hormones secretin and cholecystokinin, which is produced by the walls of the duodenum upon detection of acid food, proteins and fats. Pancreatic secretion consists of an aqueous bicarbonate component from the duct cells and enzymatic component from the acinar cells.

External links

• "Pancreatic juice" at Dorland's Medical Dictionary

• Physiology at MCG 6/6ch4/s6ch4_18
• Diagram at uta.edu

v d e Digestive system, physiology: gastrointestinal physiology GI tract Upper GI Exocrine Chief cells (Pepsinogen) · Parietal cells (Gastric acid, Intrinsic factor) · Goblet cells (Mucus) Processes Swallowing · Vomiting Fluids Saliva · Gastric juice Lower GI Enteric nervous system Meissner's plexus · Auerbach's plexus Endocrine/paracrine G cells (gastrin) · D cells (somatostatin) · ECL cells (Histamine) enterogastrone: I cells (CCK) · K cells (GIP) · S cells (secretin) Enteroendocrine cells · Enterochromaffin cell · APUD cell Fluids Intestinal juice Processes Segmentation contractions · Migrating motor complex · Borborygmus · Defecation Either/both Processes Peristalsis (Interstitial cell of Cajal · Basal electrical rhythm) · Gastrocolic reflex · Digestion Accessory Fluids Bile · Pancreatic juice Processes Enterohepatic circulation Abdominopelvic Peritoneal fluid M: DIG anat(t, g, p)/phys/devp/enzy noco/cong/tumr, sysi/epon proc, drug(A2A/2B/3/4/5/6/7/14/16), blte

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