I believe the movie your looking for is A Perfect Getaway (2009)
with Milla Jovovich and Timothy Olephant. Here is a little synopsis
of the story
For their honeymoon, newlyweds Cliff and Cydney head to the
tropical islands of Hawaii. While journeying through the
paradisaical countryside the couple encounters Kale and Cleo, two
disgruntled hitchhikers and Nick and Gina, two wild but
well-meaning spirits who help guide them through the lush jungles.
The picturesque waterfalls and scenic mountainsides quickly give
way to terror when Cliff and Cydney learn of a grisly murder that
occurred nearby and realize that they're being followed by chance
acquaintances that suspiciously fit the description of the
killers