Perutz is a surname and may refer to:
- Leo Perutz (1882– 1957), Czech-Austrian novelist and mathematician
- Max Ferdinand Perutz (1914–2002), Austrian-British molecular biologist
- Robin Perutz, son of Max, chemist
- Otto Perutz (1847-1922), Czech-German engineer
See also
- Peretz
- Perutz-Photowerke, a German manufacturer of photographic film founded by Otto Perutz
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