An enzyme that catalyzes the production of glucose phosphate from glycogen and inorganic phosphate.
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Results for phosphorylase
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On this page:
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n.
Sports Science and Medicine:
phosphorylase
An enzyme that plays a key part in regulating glycolysis in muscle cells. It catalyses the conversion of glycogen to a phosphate of glucose. Phosphorylase is activated during exercise by increased amounts of AMP, calcium, and epioephrine. Those with McArdle's disease (a deficiency in phosphorylase or phosphofructokinase) have an impaired ability to utilize intramuscular glycogen as an energy substrate.
Medical Dictionary:
phos·pho·ryl·ase
(fŏs'fər-ə-lās', -lāz')n.
An enzyme that catalyzes the production of glucose phosphate from glycogen and inorganic phosphate.
Veterinary Dictionary:
phosphorylase
A key regulatory enzyme that, in the presence of inorganic phosphate, catalyzes the removal of one glucose unit from glycogen to glucose-1-phosphate.
- citrulline p. — see ornithine carbamoyl transferase.
- p. kinase — an enzyme that activates phosphorylase by catalyzing the phosphorylation of serine. See also kinase.
Wikipedia:
phosphorylase
Phosphorylase is a family of
Function
More generally, phosphorylases are enzymes that catalyze the addition of a phosphate group from an inorganic phosphate
(phosphate+hydrogen) to an acceptor. Do not confuse this enzyme with a phosphatase or a
Types
The phosphorylases are named by prepending the name of the substrate, e.g. glycogen
phosphorylase,
All known phosphorylases share catalytic and structural properties [1].
Activation
Phosphorylase a is the active form of glycogen phosphorylase that is derived from the phosphorylation of the inactive form, phosphorylase b.
Pathology
Some disorders are related to phosphorylases:
Glycogen storage disease type V - muscle glycogen- Glycogen storage disease type VI - liver glycogen
External links
| Transferases: glycosyltransferases (EC 2.4) | |
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| 2.4.1 - glucosyltransferase |
Phosphorylase
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| 2.4.1 - other |
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| 2.4.2 - |
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| 2.4.2 - other |
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Copyrights:
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 | Dictionary. The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2007. Published by Houghton Mifflin Company. All rights reserved. Read more |
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| Sports Science and Medicine. The Oxford Dictionary of Sports Science & Medicine. Copyright © Michael Kent 1998, 2006, 2007. All rights reserved. Read more |
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| Medical Dictionary. The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Read more |
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| Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved. Read more |
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| Wikipedia. This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Phosphorylase". Read more |
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Mentioned In:
- McArdle's syndrome (medicine)
- ochratoxin A (biochemistry)
- Edmond H. Fischer (American biochemist)
- Severo Ochoa (Spanish–American biochemist)
- Glycogen Storage Diseases: Causes and symptoms
- glycogenolysis
- Glycogen
- purine
- Muscle Spasms and Cramps: Causes and symptoms
- Gerty T. Cori
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