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photosensitivity

 
Medical Encyclopedia: Photosensitivity

Definition

Photosensitivity is any increase in the reactivity of the skin to sunlight.

Description

The skin is a carefully designed interface between our bodies and the outside world. It is infection-proof when intact, nearly waterproof, and filled with protective mechanisms. Sunlight threatens the health of the skin. Normal skin is highly variable in its ability to resist sun damage. Natural skin pigmentation is its main protection. The term photosensitivity refers to any increase beyond what is considered normal variation.

— J. Ricker Polsdorfer, MD



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Dictionary: pho·to·sen·si·tiv·i·ty   ('tō-sĕn'sĭ-tĭv'ĭ-tē) pronunciation
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n., pl., -ties.
  1. Sensitivity or responsiveness to light.
  2. Medicine. An abnormally heightened response, especially of the skin, to sunlight or ultraviolet radiation, caused by certain disorders or chemicals and characterized by a toxic or allergic reaction.

Sports Science and Medicine: photosensitivity
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A heightened sensitivity to light, which can be caused by certain medications, drugs, or other chemicals. It may lead to phototoxicity.

Veterinary Dictionary: photosensitivity
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The state of being photosensitive.

Wikipedia: Photosensitivity
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Photosensitivity is the amount to which an object reacts upon receiving photons, especially visible light.

Contents

Interpretation in medicine

Sensitivity of the skin to a light source can take various forms. People with particular skin types are more sensitive to sunburn. Particular medications make the skin more sensitive to sunlight; these include most of the tetracycline antibiotics, heart drugs amiodarone, and sulfonamides. Particular conditions lead to increased light sensitivity. Patients with systemic lupus erythematosus experience skin symptoms after sunlight exposure; some types of porphyria are aggravated by sunlight. A rare hereditary condition xeroderma pigmentosum (a defect in DNA repair) is thought to increase the risk of UV-light-exposure-related cancer by increasing photosensitivity. Consumption of green or dried buckwheat plants results in severe photosensitivity in horses. The ripe seed has no effect.[1]

While the term "photoallergy" or "sunlight allergy" is commonly employed in many of the conditions mentioned, there is in fact no actual allergy in the technical sense of the word if the reaction is a purely photoirritant type. Skin photoallergies occur when light is required to trigger the interaction between a chemical material in the skin and host tissues with the resultant formation of an antigen that is recognized by the host immune system. Typically, these types of reaction are similar to a hapten-carrier reaction in contact sensitization reactions with the exception that light is needed to trigger the binding of the hapten to the host carrier molecule. On the person, photoallergy will result in a redish pink blotchy rash that can spread to parts of the body that weren't exposed to sunlight. It itches quite a bit, and has a painful prickling sensation to it as well. There is also phototoxic reactions, that are a bit like sunburn, but a bit more severe.

Interpretation in electronic engineering

Certain electronic devices, such as photodiodes and charge-coupled devices, are designed to be sensitive to light. They are constructed to take advantage of the photoelectric effect, the emission of electrons from matter upon the absorption of electromagnetic radiation. When light (one form of electromagnetic radiation) impinges on the active surface of such a device, electrical current flowing through or electrical charge stored in the device will increase or decrease in proportion to the intensity and wavelength of the light, although there is an upper limit to the amount of electrons released vs the increased intensity of the light, this comes out of quantum mechanics. This trait allows the device to perform regulating and sensing functions of many kinds. For example, a photoresistor circuit may sense ambient light to turn on a street lamp at dusk. Digital cameras use charge-coupled devices whose extreme sensitivity to light allows them to convert incoming photons into varying electrical charges with great accuracy. The varying charges are then encoded in a binary file which can be stored and later viewed on a computer screen or other medium.

Interpretation in chemistry

Chemicals that are photosensitive may undergo chemical reactions when exposed to light. These chemicals, such as hydrogen peroxide and many prescription drugs, are stored in tinted or opaque containers until they are needed to prevent photodegradation. Devices that are photosensitive include the human retina and photographic film; their photosensitive materials undergo a chemical reaction when struck by light.

Typical substances that are photosensitive are alkali salts and silver halides.

See also

External links

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Copyrights:

Medical Encyclopedia. © 2006 through a partnership of Answers Corporation. All rights reserved.  Read more
Dictionary. The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2009. Published by Houghton Mifflin Company. All rights reserved.  Read more
Sports Science and Medicine. The Oxford Dictionary of Sports Science & Medicine. Copyright © Michael Kent 1998, 2006, 2007. All rights reserved.  Read more
Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved.  Read more
Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "Photosensitivity" Read more