You mean your plaintext message the yes you can but you have to
separate it with an x when you put letters in pairs, but in a key
no.
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The Playfair Cipher is useful because it requires no special
equipment to use. However, it was invented in 1854 and is
antiquated and rarely used in the present.
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Giles Playfair's birth name is Giles William Playfair.