A granuloma is a small clump of cells that forms when the immune system tries to fight off a harmful substance but cannot remove it from the body.

A necrotizing granuloma is an area of inflammation in which tissue has died. Necrotizing means dying or decaying. See: Necrotic

Tuberculosis and Wegener's granulomatosisare conditions that cause necrotizing granulomas.

Granuloma

Review Date: 08/17/2011

David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Lymphadenitis is inflammation of a lymph node.

Typically inflammation of the lymph nodes are signs of immune-activation in the local-area the lymph node supplies. Often this is seen in enlarged, tender lymph nodes.

The state is called "lymphadenopathy" - meaning basically "disease of the lymph node(s)". Though lymphadenopathy is quite common in states of heightened immune activity (some may know it from the tender lymph-nodes under the jaw when you have a sore throat), it can also be evident of more serious systemic disease, and if persistent for more than 7-10 days should be seen by a doctor.

Inflammation of lymph nodes are simply a response to the activation of that area of the lymphatic system, due to infection of some sort. You have dozens of lymph nodes throughout your body, and several "clearing houses", if you will, that help to filter lymphatic fluid and redistribute it within the lymphatic system.

When you get sick or have injury, your body initiates an increase in white blood cells and "T" cells, which both assist in fighting the infection or injury. Those cells are distributed through the blood, and filtered through the lymphatic system. Thus, it is similar to adding sugar to water, then using a coffee filter to strain it. The sugar that collects in the coffee filter is similar to the white blood cells and lymphatic debris that collect in the lymph nodes, which is what causes the inflammation.

The state is called "lymphadenopathy" - meaning basically "disease of the lymph node(s)". Though lymphadenopathy is quite common in states of hightened immune activity (some may know it from the tender lymph-nodes under the jaw when you have a sore throat), it can also be evident of more serious systemic disease, and if persistent for more than 7-10 days should be seen by a doctor.

lymphadenitis

Inflammation of lymph nodes are simply a response to the activation of that area of the lymphatic system, due to infection of some sort. You have dozens of lymph nodes throughout your body, and several "clearing houses", if you will, that help to filter lymphatic fluid and redistribute it within the lymphatic system.

When you get sick or have injury, your body initiates an increase in white blood cells and "T" cells, which both assist in fighting the infection or injury. Those cells are distributed through the blood, and filtered through the lymphatic system. Thus, it is similar to adding sugar to water, then using a coffee filter to strain it. The sugar that collects in the coffee filter is similar to the white blood cells and lymphatic debris that collect in the lymph nodes, which is what causes the inflammation.
lymphadenitis