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Polysome

 
(′päl·i′sōm)

(cell and molecular biology) A complex of ribosomes bound together by a single messenger ribonucleic acid molecule. Also known as polyribosome.


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Polyribosome. See also ribosome.

Wikipedia: Polysome
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Polyribosomes (or polysomes) are a cluster of ribosomes, bound to a mRNA molecule, first discovered and characterized by Jonathan Warner, Paul Knopf, and Alex Rich in 1963.[1] Polyribosomes read one strand of mRNA simultaneously, helping to synthesize the same protein at different spots on the mRNA, mRNA being the "messenger" in the process of protein synthesis. They may appear as clusters, linear arrays, or rosettes in routine: this is aided by the fact that mRNA is able to be twisted into a circular formation, creating a cycle of rapid ribosome recycling, and utilization of ribosomes. 5' 7-methylguanosine cap and 3' polyA tail aids in this process.[2]

Polyribosomes can be found in three forms: free, cytoskeletal bound and membrane bound.

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References

  1. ^ Warner JR, Knopf PM, Rich A (1963). "A multiple ribosomal structure in protein synthesis". Proc. Natl. Acad. Sci. U.S.A. 49: 122–9. doi:10.1073/pnas.49.1.122. PMID 13998950. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=13998950.  Summary
  2. ^ Harvey Lodish et al. (1999). "4.5. Stepwise Formation of Proteins on Ribosomes". Molecular cell biology. New York: Scientific American Books. ISBN 0-7167-3136-3. 

 
 
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polyribosome
free ribosome (cell and molecular biology)
nucleic acid (in biology)

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Sci-Tech Dictionary. McGraw-Hill Dictionary of Scientific and Technical Terms. Copyright © 2003, 1994, 1989, 1984, 1978, 1976, 1974 by McGraw-Hill Companies, Inc. All rights reserved.  Read more
Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved.  Read more
Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "Polysome" Read more