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progressive systemic sclerosis

 

n.

A systemic disease marked by formation of hyalinized and thickened collagenous fibrous tissue, with thickening and adhesion of skin to underlying tissues, especially of the hands and face. Also called scleroderma.

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Medical Dictionary. The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company Read more