biomolecule called prostacyclin? what is the functional group?

von Willebrand factor

This is prevented by prostacyclin (prostaglandin I2, PGI2) and nitric oxide released from the endothelium.

Gabor M. Rubanyi has written:

'The endothelium in clinical practice' -- subject(s): Pathophysiology, Physiopathology, Prostacyclin, Endothelium, Endothelins, Therapy, Thromboxanes, Vascular endothelium, Physiology, Heart Diseases

They are synthesized in the cell from the essential fatty acids (EFAs).

An intermediate arachidonic acid is created from diacylglycerol via phospholipase-A2, then brought to either the cyclooxygenase pathway or the lipoxygenase pathway to form either prostaglandin and thromboxane or leukotriene respectively. The cyclooxygenase pathway produces thromboxane, prostacyclin and prostaglandin D, E and F. Alternatively, the lipoxygenase enzyme pathway is active in leukocytes and in macrophages and synthesizes leukotrienes.

Dr.Fabianski Benjamin