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Prothrombinase converts prothrombin into enzyme thrombin.

Q: What is used in blood clotting?

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Prothrombinase converts prothrombin into enzyme thrombin.

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Prothrombinase converts prothrombin into enzyme thrombin.

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Jennifer Ann Crookshank has written:

'Characterization of the Fg12-prothrombinase binding protein'

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Blood is normally a liquid found in veins. When an injury occurs and blood needs to clot, three processes occur. The first process in the creation of prothrombinase which occurs when liquid blood comes in contact with a foreign body or injured tissue. The second process is prothrombin which is a plasma protein that is formed in the liver. The third process us fibrinogen which is also synthesized by the liver. Fibrinogen forms the threads that bind the clot.

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Damage to the blood vessel: when an injury occurs, damage to the walls of blood vessels in the skin or tissue releases a substance called tissue thromboplastin, almost like an SOS signal.

This substance is composed mainly of phospholipids from the damaged tissues.

The thromboplastin then triggers a cascade of enzymatic reactions among multiple blood plasma proteins called blood coagulation factors.

These reactions eventually form prothrombin activator(also called prothrombinase), which causes the prothrombin to change into the enzyme thrombin.

Thrombin initiates coagulation by converting the soluble fibrinogen into insoluble fibrin threads that will bind the clot.

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