n.
A crystalline amine, C8H12N2O2, one of several active forms of pyridoxine, important in protein metabolism.
[PYRIDOX(INE) + -AMINE.]
Dictionary:
pyr·i·dox·a·mine (pĭr'ĭ-dŏk'sə-mēn')
|
[PYRIDOX(INE) + -AMINE.]
| 5min Related Video: pyridoxamine |
| Medical Dictionary: pyr·i·dox·a·mine |
A crystalline amine that is one of several active forms of pyridoxine and is important in protein metabolism.
| Veterinary Dictionary: pyridoxamine |
One of the three active forms of vitamin B6.
| WordNet: pyridoxamine |
The noun has one meaning:
Meaning #1:
a B vitamin that is essential for metabolism of amino acids and starch
Synonyms: vitamin B6, pyridoxine, pyridoxal, adermin
| Wikipedia: Pyridoxamine |
| Pyridoxamine | |
|---|---|
| IUPAC name |
4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol
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| Identifiers | |
| CAS number | 85-87-0 |
| PubChem | 1052 |
| SMILES |
Oc1c(CN)c(cnc1C)CO
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| ChemSpider ID | 1023 |
| Properties | |
| Molecular formula | C8H12N2O2 |
| Molar mass | 168.19 g mol−1 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Pyridoxamine is one of the compounds composing vitamin B6, along with pyridoxal and pyridoxine. Pyridoxamine is converted to the biologically active form, pyridoxal 5-phosphate, and inhibits formation of advanced glycation endproducts.
Pyridoxamine is based on a pyridine ring, with hydroxyl, methyl, aminomethyl, and hydroxymethyl substituents. It differs from pyridoxine by the subsitituent at the 4-position.
Pyridoxamine is used as a dietary supplement, often as the hydrochloride salt, pyridoxamine dihydrochloride. However, in the United States, the FDA ruled in January 2009 that pyridoxamine must be regulated as a pharmaceutical drug because it is the active ingredient in Pyridorin, a drug designed to prevent the progression of diabetic nephropathy.[1] As a consequence, pyridoxamine can no longer be marketed in the United States as a dietary supplement.
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| vitamin B6 (biochemistry) | |
| pyridoxine vitamin | |
| vitamin B, vitamin B complex |
| When was pyridoxamine discovered and were there any marketed products containing pyridoxamine prior to 1994? |
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