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PKD is caused by a deficiency in the enzyme, pyruvate kinase.
Pyruvate kinase deficiency (PKD) is part of a group of disorders called hereditary nonspherocytic hemolytic anemias.
pyruvate
Yes, Mg2+ is a cofactor for the enzymes phosphofructo kinase-1, phosphoglycerate kinase, enolase, and pyruvate kinase in glycolysis.
pyruvate carboxylase and phosphoenolpyruvate carboxykinase (PEPCK)