Aspirin should not be given to children because of concerns about Reye's syndrome

As many as 30% of children and teenagers who develop Reye's syndrome die

In the United States, the most common age for Reye syndrome is six to eight years. Reye syndrome is extremely rare in individuals over the age of 18.

Diagnosis involves blood tests to determine the levels of certain liver enzymes, which are highly elevated in Reye's syndrome.

Children with flu or chicken pox should not be given bismuth subsalicylate. It can lead to Reye's syndrome