Negative and Positive blood types refer to the presence of the
Rhesus D (RhD) antigen. Rhesus is the second main blood group
typing after the A,B,O system.
e.g.
AB+ means the blood cells have A and B and RhD antigens present
on the blood cell surface.
O- means that A and B and RhD antigens are not present on the
surface of the blood cell.