ribose

 
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ribose

  ('bōs') pronunciation
n.

A pentose sugar, C5H10O5, occurring as a component of riboflavin, nucleotides, and nucleic acids.

[German, alteration of English arabinuse, a kind of sugar : (GUM) ARAB(IC) + –IN + –OSE2.]


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A water-soluble pentose, also known as D-ribose (see first structural formula), which, together with 2-deoxy-D-ribose, makes up the carbohydrate constituents of nucleic acids, which are found in all living organisms.

The universal occurrence of nucleic acids in all living cells makes this pentose highly interesting to biochemists and biologists. The type of nucleic acid that yields D-ribose is referred to as ribonucleic acid (RNA). D-Ribose is a constituent not only of the nucleic acids, but also of several vitamins and coenzymes. As in the nucleic acids, this sugar occurs in the furanose configuration (see second structural formula) in these natural products. See also Coenzyme; Deoxyribose; Nucleic acid; Vitamin.


 

A pentose (five-carbon) sugar which occurs as an intermediate in the metabolism of glucose; especially important in the nucleic acids and various coenzymes: occurs widely in foods.

 

n

A 5-carbon sugar that occurs as a component of ribonucleic acid.

 

Five-carbon sugar found in RNA. (In DNA the corresponding sugar is the closely related deoxyribose.) A ribose molecule combined with adenine, guanine, cytosine, or uracil forms a nucleoside; adding a phosphate group forms a nucleotide. The ribose of one nucleotide joins with the phosphate of the next to form the RNA backbone. Ribose phosphates are components of various coenzymes and are used by microorganisms in synthesizing histidine.

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A five-carbon sugar readily synthesized in the body and provided in small amounts by the diet from ripe fruits and vegetables. Ribose serves as an energy substrate for the resynthesis of ATP.

 
('bōs) , monosaccharide carbohydrate of universal distribution in living tissue, found in ribonucleic acid (RNA; see nucleic acid), free nucleotides, and various coenzymes. Its close relative, deoxyribose, is a constituent of deoxyribonucleic acid (DNA); ribose has one more oxygen atom in its molecule than deoxyribose. Some of the best procedures for the laboratory preparation of ribose involve the hydrolysis of yeast nucleic acid.


 

5-carbon sugar present in ribonucleic acid (RNA).

 
Wikipedia: ribose
Ribose[1]
Ribofuranose-2D-skeletal.png
IUPAC name (3R,4S,5R)-5-(Hydroxymethyl)tetrahydrofuran-2,3,4-triol
Identifiers
CAS number 200-059-4
PubChem 5779
SMILES C([C@@H]1[C@H]([C@H](C(O1)O)O)O)O
Properties
Molecular formula C5H10O5
Molar mass 150.13
Appearance White solid
Melting point

99 °C, 372 K, 210 °F

Solubility in water Very soluble
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references


Ribose (ɹˈaɪbəʊs[1], ɹˈaɪbəɹʊs[2]), primarily seen as D-ribose, is an aldopentose — a monosaccharide containing five carbon atoms, and including an aldehyde functional group in its linear form. It has the chemical formula C5H10O5, and was discovered in 1905 by Phoebus Levene.

As a component of the RNA that is used for genetic transcription, ribose is critical to living creatures. It is related to deoxyribose, which is a component of DNA. It is also a component of ATP, NADH, and several other chemicals that are critical to metabolism.

Refer to the article on deoxyribose for more information on both sugars, how they relate to each other, and how they relate to genetic material.

Isomerism

D-Ribose has the same configuration at its penultimate carbon atom as D-glyceraldehyde.

Ribose in acyclic form
Enlarge
Ribose in acyclic form


See also

References

  1. ^ Merck Index, 11th Edition, 8205.

External links



 
 

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