RISC can refer to many things. There are a few bussinesses with
that anagram. RISC can also stand for Reduced Instruction Set
Computing. It could also stand for "RNA-induced Silencing
Complex."
RISC can refer to many things. There are a few bussinesses with
that anagram. RISC can also stand for Reduced Instruction Set
Computing. It could also stand for "RNA-induced Silencing
Complex."
Certain small RNA molecules fold into loops. The Dicer enzyme
cuts them into
microRNA (miRNA). The strands then separate. An miRNA piece
attaches to a cluster
of proteins to form a silencing complex. The silencing complex
binds to and destroys
an mRNA molecule that contains a base sequence complementary to
the miRNA. In
this way, it blocks gene expression.
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RNA has been found in a panoply of human body fluids: blood,
urine, have since discovered this type of RNA silencing in many
orginisms.
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An open complexAn open complex is the complex of RNA polymerase and one DNA strand (The antisense strand) while a Closed complex is the complex of RNA Polymerase when it is bound to the double stranded DNA. The RNA Polymerase first creates the closed compex. The open complex is created when the double stranded DNA is separated to two strands.