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serology

 
(sĭ-rŏl'ə-jē) pronunciation
n., pl., -gies.
  1. The science that deals with the properties and reactions of serums, especially blood serum.
  2. The characteristics of a disease or organism shown by study of blood serums: the serology of acquired immune deficiency syndrome; the serology of mammals.
serologic se'ro·log'ic (sîr'ə-lŏj'ĭk) or se'ro·log'i·cal (-ĭ-kəl) adj.
serologically se'ro·log'i·cal·ly adv.
serologist se·rol'o·gist n.

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The division of biological science concerned with antigen-antibody reactions in serum. It properly encompasses any of these reactions, but is often used in a limited sense to denote laboratory diagnostic tests, especially for syphilis. The techniques of blood grouping have come from the study of antigen-antibody reactions in serum, as have techniques for identification of genetic polymorphism and quantitation of numerous serum proteins. With these advances came the means for developing transfusion therapy with cells and plasma. In addition, these techniques led to identification of antibodies involved in incompatibility reactions, such as in erythroblastosis fetalis, and the development of effective measures to prevent their occurrence. Further, extension of these techniques to identification of antigens on white cells led to effective methods of histocompatibility typing, facilitating organ transplantation. See also Transplantation biology.



the study of serum; in particular, the immunological phenomena involving circulating antibody that may be observed in vitro.

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A specialist in serology. An old term for immunologist.

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Serology is the scientific study of blood serum and other bodily fluids. In practice, the term usually refers to the diagnostic identification of antibodies in the serum.[1] Such antibodies are typically formed in response to an infection (against a given microorganism),[2] against other foreign proteins (in response, for example, to a mismatched blood transfusion), or to one's own proteins (in instances of autoimmune disease).

Serological tests may be performed for diagnostic purposes when an infection is suspected, in rheumatic illnesses, and in many other situations, such as checking an individual's blood type.[1] Serology blood tests help to diagnose patients with certain immune deficiencies associated with the lack of antibodies, such as X-linked agammaglobulinemia. In such cases, tests for antibodies will be consistently negative.

There are several serology techniques that can be used depending on the antibodies being studied. These include: ELISA, agglutination, precipitation, complement-fixation, and fluorescent antibodies.

Some serological tests are not limited to blood serum, but can also be performed on other bodily fluids such as semen and saliva, which have (roughly) similar properties to serum.

Serological tests may also be used forensically, generally to link a perpetrator to a piece of evidence (e.g., linking a rapist to a semen sample).

Contents

Serological surveys

Serological surveys are often used by epidemiologists to determine the prevalence of a disease in a population. Such surveys are sometimes performed by random, anonymous sampling from samples taken for other sexual tests.

See also

References

  1. ^ a b Ryan KJ, Ray CG (editors) (2004). Sherris Medical Microbiology (4th ed.). McGraw Hill. pp. 247–9. ISBN 0838585299. 
  2. ^ Washington JA (1996). Principles of Diagnosis: Serodiagnosis. in: Baron's Medical Microbiology (Baron S et al., eds.) (4th ed.). Univ of Texas Medical Branch. ISBN 0-9631172-1-1. http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mmed.section.5462. 

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Translations:

Serology

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Dansk (Danish)
n. - serologi, serumvidenskab

Nederlands (Dutch)
serologie, bloedkunde

Français (French)
n. - sérologie

Deutsch (German)
n. - Serologie, Serumkunde

Ελληνική (Greek)
n. - (ιατρ.) ορολογία, μελέτη των ορών

Italiano (Italian)
sierologia

Português (Portuguese)
n. - serelogia (m) (Med.)

Русский (Russian)
серология

Español (Spanish)
n. - serología

Svenska (Swedish)
n. - serologi

中文(简体)(Chinese (Simplified))
血清学

中文(繁體)(Chinese (Traditional))
n. - 血清學

한국어 (Korean)
n. - 혈청학, 혈청 반응 검사

日本語 (Japanese)
n. - 血清学

العربيه (Arabic)
‏(الاسم) علم المصول‏

עברית (Hebrew)
n. - ‮חקר הנוגדנים בדם והאפקטים שלהם‬


 
 
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Copyrights:

American Heritage Dictionary. The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2009. Published by Houghton Mifflin Company. All rights reserved.  Read more
McGraw-Hill Science & Technology Encyclopedia. McGraw-Hill Encyclopedia of Science and Technology. Copyright © 2005 by The McGraw-Hill Companies, Inc. All rights reserved.  Read more
 Oxford Dictionary of Biochemistry. Oxford University Press. Oxford Dictionary of Biochemistry and Molecular Biology © 1997, 2000, 2006 All rights reserved.  Read more
Saunders Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved.  Read more
Random House Word Menu. © 2010 Write Brothers Inc. Word Menu is a registered trademark of the Estate of Stephen Glazier. Write Brothers Inc. All rights reserved.  Read more
Wikipedia on Answers.com. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article Serology Read more
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