Both a silent and missense mutation is a change in one nucleotide. However, a silent mutation still codes for the same amino acid, but a missense mutation codes for a different amino acid. This means that a silent mutation will have no affect on the resulting protein, but a missense mutation will.

Still, it is not guaranteed that a a missense mutation will result in a disfunction of created protein, as long as it is not occurring in the activation site.

A silent mutation

Well a Silent Mutation does not affect anything so it isn't bad so its a good mutation.

Some subsitituations are called silent mutation because owing to the reduncancy of the genetic code, they have NO EFFECT on the coded protien.. and there you got -- Silent mutation by base-pair substition.. Hope that helps.. Got it out of my AP Biology Textbook.

a mutation that does not affect protein production.