Hip ulcer with massive skin and buttock drainage

Lymph nodes are small glands that function to filter the lymph (excess plasma that circulates around tissues in capillary beds); they are often the first place where infections and metastatic cancers are found. The sinuses of a lymph node are small open pockets between the lymphocytes where fluid can accumulate. Histiocytosis is an abnormal accumulation of histiocytes (also called macrophages).

Therefore, lymph node sinus histiocytosis is an abnormal accumulation of macrophages within the open spaces of a lymph node. There are many potential causes of this, ranging from chronic infection to cancer. Your doctor will need to explain what the most likely cause is as well as treatment options and likely outcomes.

Persistent Generalized Lymphadenopathy

No. But it can coexist with a swelling of the thyroid which may superficially look a bit like lymphadenopathy.

the term for englared or palpable lymph nodes is lymphadenopathy.