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Skin lesion

 
Medical Encyclopedia: Skin Lesions

Definition

A skin lesion is a superficial growth or patch of the skin that does not resemble the area surrounding it.

Description

Skin lesions can be grouped into two categories: primary and secondary. Primary skin lesions are variations in color or texture that may be present at birth, such as moles or birthmarks, or that may be acquired during a person's lifetime, such as those associated with infectious diseases (e.g., warts, acne, or psoriasis), allergic reactions (e.g., hives or contact dermatitis), or environmental agents (e.g., sunburn, pressure, or temperature extremes). Secondary skin lesions are those changes in the skin that result from primary skin lesions, either as a natural progression or as a result of a person manipulating (e.g., scratching or picking at) a primary lesion.

The major types of primary lesions are:

  • Macule. A small, circular, flat spot less than 0.4 in (1 cm) in diameter. The color of a macule is not the same as that of nearby skin. Macules come in a variety of shapes and are usually brown, white, or red. Examples of macules include freckles and flat moles. A macule more than 0.4 in (1 cm) in diameter is called a patch.
  • Vesicle. A raised lesion less than 0.2 in (5 mm) across and filled with a clear fluid. Vesicles that are more than0.2 in (5 mm) across are called bullae or blisters. These lesions may may be the result of sunburns, insect bites, chemical irritation, or certain viral infections, such as herpes.
  • Pustule. A raised lesion filled with pus. A pustule is usually the result of an infection, such as acne, imptigeo, or boils.
  • Papule. A solid, raised lesion less than 0.4 in (1 cm) across. A patch of closely grouped papules more than0.4 in (1 cm) across is called a plaque. Papules and plaques can be rough in texture and red, pink, or brown in color. Papules are associated with such conditions as warts, syphilis, psoriasis, seborrheic and actinic keratoses, lichen planus, and skin cancer.
  • Nodule. A solid lesion that has distinct edges and that is usually more deeply rooted than a papule. Doctors often describe a nodule as "palpable," meaning that, when examined by touch, it can be felt as a hard mass distinct from the tissue surrounding it. A nodule more than 0.8 in (2 cm) in diameter is called a tumor. Nodules are associated with, among other conditions, keratinous cysts, lipomas, fibromas, and some types of lymphomas.
  • Wheal. A skin elevation caused by swelling that can be itchy and usually disappears soon after erupting. Wheals are generally associated with an allergic reaction, such as to a drug or an insect bite.
  • Telangiectasia. Small, dilated blood vessels that appear close to the surface of the skin. Telangiectasia is often a symptom of such diseases as rosacea or scleroderma.

The major types of secondary skin lesions are:

  • Ulcer. Lesion that involves loss of the upper portion of the skin (epidermis) and part of the lower portion (dermis). Ulcers can result from acute conditions such as bacterial infection or trauma, or from more chronic conditions, such as scleroderma or disorders involving peripheral veins and arteries. An ulcer that appears as a deep crack that extends to the dermis is called a fissure.
  • Scale. A dry, horny build-up of dead skin cells that often flakes off the surface of the skin. Diseases that promote scale include fungal infections, psoriasis, and seborrheic dermatitis.
  • Crust. A dried collection of blood, serum, or pus. Also called a scab, a crust is often part of the normal healing process of many infectious lesions.
  • Erosion. Lesion that involves loss of the epidermis.
  • Excoriation. A hollow, crusted area caused by scratching or picking at a primary lesion.
  • Scar. Discolored, fibrous tissue that permanently replaces normal skin after destruction of the dermis. A very thick and raised scar is called a keloid.
  • Lichenification. Rough, thick epidermis with exaggerated skin lines. This is often a characteristic of scratch dermatitis and atopic dermatitis.
  • Atrophy. An area of skin that has become very thin and wrinkled. Normally seen in older individuals and people who are using very strong topical corticosteroid medication.

— Bridget Travers



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Wikipedia: Skin lesion
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A skin lesion is a superficial growth or patch of the skin that does not resemble the area surrounding it. They may take the form of bumps, blisters, or general sores. While many are benign (such as moles or freckles) some are the result of toxins (such as mosquito bites) or diseases (such as chicken pox or psoriasis)

Most dermatoses present with skin lesions of more or less distinct characteristics. Macroscopically, these original lesions are known as the "primary lesion", and identification of such lesions is "...the most important aspect of dermatologic examination."[1] However, these lesions may continue to develop or be modified by regression or trauma, producing "secondary lesions".[1] Additionally, on the microscopic level, these lesions can also be characterized by a distinct set of vocabulary.[2]

Contents

Lack of standardization

The lack of standardization of basic dermatologic terminology has been one of the principal barriers to successful communication among physicians in describing skin lesions.[3] For example, in different dermatologic texts, the papule is variously described as no greater than 1 centimetre (0.39 in) in size, less than 0.5 centimetres (0.20 in), smaller than a pea, or ranging in size from a pinhead to that of a split pea.[3] In 1987, the International League of Dermatologic Societies published a glossary of basic lesions that has been a step towards standardization of this basic nomenclature,[4] but there is still no strict set of definitions that have been universally agreed upon.[3]

Macroscopic nomenclature

Primary lesions

Secondary lesions

Microscopic nomenclature

Evolution

While most dermatoses present with skin lesions of more or less distinct characteristics, skin lesions do evolve through time.[5]

See also

References

  1. ^ a b James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Philadelphia: Saunders Elsevier. p. 15. ISBN 0721629210.  LCCN 2005-057588
  2. ^ Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson, eds (2005). Robbins and Cotran pathologic basis of disease. illustrations by James A. Perkins (7th ed.). Philadelphia: Elsevier Saunders. p. 1230. ISBN 0721601871.  LCCN 2004-046835
  3. ^ a b c Freedberg, Irwin M.; et al, eds (2003). Fitzpatrick's Dermatology in General Medicine (6th ed.). New York: McGraw-Hill Professional. p. 13. ISBN 0071380760.  LCCN 2002-021932
  4. ^ Winkelmann, R. K. (1987). "Glossary of basic dermatology lesions. The International League of Dermatological Societies Committee on Nomenclature." (in English, German, Spanish). Acta dermato-venereologica. Supplementum (Sweden: The Society for Publication of Acta Dermato-Venereologica) 130: 13. ISSN 0365-8341. PMID 3321818. 
  5. ^ Rapini, Ronald P. (2005). Practical dermatopathology. St. Louis, Missouri: Elsevier Mosby. ISBN 0-323-01198-5.  LCCN 2005-047780

 
 

 

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