| Dictionary: sodium fluoride |
| 5min Related Video: sodium fluoride |
| Chemistry Dictionary: sodium fluoride |
A crystalline compound, NaF, soluble in water and very slightly soluble in ethanol; cubic; r.d. 2.56; m.p. 993°C; b.p. 1695°C. It occurs naturally as villiaumite and may be prepared by the reaction of sodium hydroxide or of sodium carbonate with hydrogen fluoride. The reaction of sodium fluoride with concentrated sulphuric acid may be used as a source of hydrogen fluoride. The compound is used in ceramic enamels and as a preservative agent for fermentation. It is highly toxic but in very dilute solution (less than 1 part per million) it is used in the fluoridation of water for the prevention of tooth decay on account of its ability to replace OH groups with F groups in the material of dental enamel.
| Dental Dictionary: sodium fluoride |
A white, odorless powder used in 2% aqueous solution and applied topically to teeth as a caries-preventing agent; used as 33% NaF in kaolin and glycerin as a desensitizing agent for hypersensitive dentin. In drinking water, one part per million of NaF is used as a caries-prophylactic substance.
| Drug Info: Sodium Fluoride |
Brand names: Flourigard®, Fluorinse®, Fluoritab®, Fluorodex®, Flura-Drops®, Flura-Tab®, Karidium®, Luride®, Pediaflor®, PreviDent®
Sodium Fluoride oral solution
What is sodium fluoride oral solution?
SODIUM FLUORIDE (Pediaflor®, Luride®, Fluoritab®, Flura-Drops®, Karidium®) is a mineral that strengthens tooth enamel and helps to prevent dental decay. Fluoride also helps to decrease sensitivity of the teeth. Fluoride, in small amounts, also helps maintain healthy bones. Most natural water supplies contain some fluoride and fluoride may be added to the water. Additional fluoride may be necessary in some cases. Generic sodium fluoride dental rinse is not available. Generic sodium fluoride oral solution is available.What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:How should I take this medicine?
Sodium fluoride oral solution is taken by mouth. Follow the directions on the prescription label. Drop the solution directly into the mouth using the dropper provided, or add to fruit juice or food that does not contain calcium. Do not take your medicine more often than directed.What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.What drug(s) may interact with sodium fluoride?
aluminum saltsWhat should I watch for while taking sodium fluoride?
Do not take this solution unless you are sure you need extra fluoride. Ask your dentist or health care professional for advice, especially if you move to a new area where the amount of fluoride in the water may be different.What side effects may I notice from taking sodium fluoride?
Recommended doses of sodium fluoride produce few side effects. Serious side effects can occur with overuse of sodium fluoride and include:Where can I keep my medicine?
Keep out of the reach of children in a container that small children cannot open.Last updated: 3/12/2004 6:16:00 PM
Important Disclaimer: The drug information provided here is for educational purposes only. It is intended to supplement, not substitute for, the diagnosis, treatment and advice of a medical professional. This drug information does not cover all possible uses, precautions, side effects and interactions. It should not be construed to indicate that this or any drug is safe for you. Consult your medical professional for guidance before using any prescription or over the counter drugs.
| Wikipedia: Sodium fluoride |
| Sodium fluoride | |
|---|---|
| IUPAC name |
Sodium fluoride
|
| Other names | Florocid |
| Identifiers | |
| CAS number | 7681-49-4 |
| PubChem | 5235 |
| EC number | 231-667-8 |
| UN number | 1690 |
| RTECS number | WB0350000 |
| Properties | |
| Molecular formula | NaF |
| Molar mass | 41.988713 g/mol |
| Appearance | White solid |
| Odor | odorless |
| Density | 2.558 g/cm3 |
| Melting point |
993 °C |
| Boiling point |
1695 °C |
| Solubility in water | 4.13 g/100 g (25 °C) |
| Solubility | soluble in HF insoluble in ethanol |
| Hazards | |
| MSDS | Sodium fluoride MSDS |
| EU Index | 009-004-00-7 |
| EU classification | Toxic (T) Irritant (Xi) |
| R-phrases | R25, R32, R36/38 |
| S-phrases | (S1/2), S22, S36, S45 |
| NFPA 704 | |
| Flash point | Non-flammable |
| LD50 | 52–200 mg/kg (oral in rats, mice, rabbits)[1] |
| Related compounds | |
| Other anions | Sodium chloride Sodium bromide Sodium iodide |
| Other cations | Lithium fluoride Potassium fluoride Rubidium fluoride Caesium fluoride |
| Related compounds | TASF reagent |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
|
| Infobox references | |
Sodium fluoride is the inorganic compound with the formula NaF. This colorless solid is a source of the fluoride ion in diverse applications. Sodium fluoride is less expensive and less hygroscopic than the related salt potassium fluoride.
Contents |
Sodium fluoride is an ionic compound, dissolving to give separated Na+ and F− ions. It crystallizes in the cubic (sodium chloride) motif where both Na+ and F− occupy octahedral coordination sites.[2][3]
The mineral form of NaF, villiaumite, is moderately rare. It is known from plutonic nepheline syenite rocks.[4]
NaF is prepared by neutralizing hydrofluoric acid or hexafluorosilicic acid (H2SiF6), coproducts of the production of superphosphate fertilizer. Neutralizing agents include sodium hydroxide and sodium carbonate. Alcohols are sometimes used to precipitate the NaF:
From solutions containing HF, sodium fluoride precipitates as the bifluoride salt NaHF2. Heating the latter releases HF and gives NaF.
In a 1986 report, the annual, worldwide consumption of NaF was estimated to be several million tonnes.[5]
Fluoride salts are used to enhance the strength of teeth by the formation of fluorapatite, a naturally occurring component of tooth enamel. Originally, sodium fluoride was used to fluoridate water; however, hexafluorosilicic acid (H2SiF6) and its salt sodium hexafluorosilicate (Na2SiF6) are more commonly used additives, especially in the United States.[citation needed] Toothpaste often contains sodium fluoride to prevent cavities.[6]
Alternatively, sodium fluoride is used as a cleaning agent, e.g. as a "laundry sour."[5] A variety of specialty chemical applications exist in synthesis and extractive metallurgy. The fluoride is the reagent for the synthesis of fluorocarbons. Representative substrates include electrophilic chlorides including acyl chlorides, sulfur chlorides, and phosphorus chloride.[7] Like other fluorides, sodium fluoride finds use in desilylation in organic synthesis.
In medical imaging, fluorine-18-labelled sodium fluoride is used in positron emission tomography (PET). Relative to conventional bone scintigraphy carried out with gamma cameras or SPECT systems, PET offers more sensitivity and spatial resolution. A disadvantage of PET is that fluorine-18 labelled sodium fluoride is less widely available than conventional technetium-99m-labelled radiopharmaceuticals.
Sodium fluoride is used to conserve tissue samples in biochemistry and medicinal testing as fluoride ions stop glycolysis by inhibiting the enzyme enolase[citation needed]. Sodium fluoride is often used together with iodoacetic acid, which inhibits the enzyme aldolase[citation needed]. It also is used in RIPA lysis buffer as phosphatase inhibitor along with Na3VO4.
Sodium fluoride is classed as toxic by both inhalation (of dusts or aerosols) and ingestion.[8] In high enough doses, it has been shown to affect the heart and circulatory system, and the lethal dose for a 70 kg human is estimated at 5–10 g.[5]
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This entry is from Wikipedia, the leading user-contributed encyclopedia. It may not have been reviewed by professional editors (see full disclaimer)
| villiaumite | |
| fluoridated salt | |
| sodium halide (inorganic chemistry) |
| What is the difference between stannous fluoride and sodium fluoride? Read answer... | |
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| What are the uses of sodium fluoride in general? Read answer... |
| What are the disadvantages of sodium fluoride in water? | |
| Chemical formula for sodium fluoride? | |
| What is Boiling point of sodium fluoride? |
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