Brand names: Nexavar®
- Drug Forms:
- Sorafenib oral tablets (below)
- Sorafenib tosylate Oral tablet
- Español:
- Sorafenib Tosilato, Tableta oral
Sorafenib oral tablets
What are Sorafenib oral tablets?
SORAFENIB (Nexavar®) is a medicine used to help treat cancer. It is used for renal (kidney) cancer, and might be used to treat other cancers as well. Generic sorafenib tablets are not available.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
bleeding problems
dental disease
infection (especially cold sores or shingles)
heart disease (like heart failure)
jaundice
kidney disease
liver disease
an unusual or allergic reaction to sorafenib, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should this medicine be used?
Take this medicine by mouth. You should take it on an empty stomach, either one hour before eating or two hours after eating. Follow the directions on the prescription label. Do not take your medicine more often than directed.
Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
What drug(s) may interact with Sorafenib?
carbamazepine
dexamethasone
docetaxel
doxorubicin
fluorouracil
irinotecan
phenobarbital
phenytoin
rifabutin
rifampicin
rifampin
St. John's wort or any herbal products containing St. John's wort
warfarin
Tell your prescriber or health care professional about all other medicines that you are taking, including nonprescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
What should I watch for while taking Sorafenib?
Visit your prescriber or health care professional for checks on your progress. You will need to have regular blood checks. The side effects of this medicine may continue after you finish your treatment; report side effects promptly.
This medicine will decrease your body's ability to fight infections. Call your prescriber or health care professional if you have a fever, chills, sore throat, or other symptoms of a cold or flu. Do not treat these symptoms yourself. Try to avoid being around people who are sick. This medicine may increase your risk to bruise or bleed. Call your prescriber or health care professional if you notice any unusual bleeding. Be careful not to cut, bruise or injure yourself because you may get an infection and bleed more than usual.
Be careful brushing and flossing your teeth or using a toothpick while taking this medicine because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are taking sorafenib.
Do not have any vaccinations without your prescriber's approval and avoid anyone who has recently had the oral polio vaccine.
There is a risk of birth defects if sorafenib is given during pregnancy. Women should not become pregnant while being treated with this medicine. Women should use effective birth control while taking sorafenib and for at least 2 weeks after stopping treatment.
If you are going to have surgery or any other procedures, tell your doctor you are taking sorafenib.
Sorafenib can cause high blood pressure especially during the first 6 weeks of therapy. Your prescriber or health care professional will monitor your blood pressure. Call your prescriber of health care professional if you have dizziness or episodes of lightheadedness.
Rarely, heart attack has been reported during sorafenib therapy. Notify your prescriber or health care professional immediately if you have chest pain, tightness, or excessive sweating. Call 911 if urgent care is required.
What side effects may I notice from receiving Sorafenib?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
dizziness
fever or chills, sore throat
pain, tingling, numbness in the hands or feet
redness, blistering, peeling or loosening of the skin, including inside the mouth
shortness of breath, chest pain, swelling in a leg
unusual bleeding or bruising
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
decreased appetite
diarrhea
dry skin
hair loss
mouth sores
nausea
stomach pain
Where can I keep my medicine?
Keep out of the reach of children in a container that small children cannot open.
Last updated: 12/21/2005 5:18:00 PM
Important Disclaimer: The drug information provided here is for educational purposes only. It is intended to supplement, not substitute for, the diagnosis, treatment and advice of a medical professional. This drug information does not cover all possible uses, precautions, side effects and interactions. It should not be construed to indicate that this or any drug is safe for you. Consult your medical professional for guidance before using any prescription or over the counter drugs.




