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sulfadiazine

 
Dictionary: sul·fa·di·a·zine   (sŭl'fə-dī'ə-zēn') pronunciation
 
n.

A sulfa drug, C10H10N4O2S, used in the treatment of toxoplasmosis and other infections.


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Drug Info: Sulfadiazine
 

Chemical formula:



Sulfadiazine Oral tablet

What is this medicine?

SULFADIAZINE is an sulfonamide antibiotic. It is used to treat many different kinds of bacterial infections, like those of the brain, ears, and urinary tract. It is also used to prevent infections in people who are at risk. It will not work for colds, flu, or other viral infections.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
• blood disorders
• glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency)
• kidney disease
• liver disease
• porphyria
• an unusual or allergic reaction to sulfadiazine, sulfa drugs, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed. Take all of your medicine as directed even if you think you are better. Do not skip doses or stop your medicine early.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 2 months old for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
• aminobenzoate potassium

This medicine may also interact with the following medications:
• aspirin and aspirin-like drugs
• diuretics like hydrochlorothiazide
indomethacin
• medicines for diabetes
• medicines for gout
methotrexate
probenecid
warfarin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not improve. You may need to have blood work done while you are taking this medicine.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Drink several glasses of water a day. This will help to reduce possible kidney problems.

This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
• allergic reactions like skin rash or hives, swelling of the face, lips, or tongue
• bluish fingernails or lips
• breathing problems
• fever or chills, sore throat
• irregular heartbeat, chest pain
• joint or muscle pain
• red pinpoint spots on skin
• redness, blistering, peeling or loosening of the skin, including inside the mouth
• trouble passing urine or change in the amount of urine
• unusual bleeding or bruising
• unusually weak or tired
• yellowing of eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
• diarrhea
• dizziness
• headache
• loss of appetite
• nausea, vomiting
• nervousness

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light. Keep container tightly closed. Throw away any unused medicine after the expiration date.

Last updated: 7/1/2002

Important Disclaimer: The drug information provided here is for educational purposes only. It is intended to supplement, not substitute for, the diagnosis, treatment and advice of a medical professional. This drug information does not cover all possible uses, precautions, side effects and interactions. It should not be construed to indicate that this or any drug is safe for you. Consult your medical professional for guidance before using any prescription or over the counter drugs.

 
Veterinary Dictionary: sulfadiazine
Top

A rapidly absorbed and readily excreted sulfonamide antibacterial agent. Used commonly in triple-sulfa preparations. The sodium salt is used intravenously.

  • silver s. — see silver sulfadiazine.
  • sodium s. — an antibacterial compound used intravenously.
  • s.–trimethoprim — a very popular combination of a potentiated sulfonamide because of its broad antibacterial spectrum and its small dose rate.
 
Wikipedia: Sulfadiazine
Top
Sulfadiazine
Systematic (IUPAC) name
4-amino-N-pyrimidin- 2-yl-benzenesulfonamide
Identifiers
CAS number 68-35-9
ATC code J01EC02
PubChem 5215
DrugBank APRD00190
Chemical data
Formula C10H10N4O2S 
Mol. mass 250.278 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status

Approved Drug

Routes Cream

Sulfadiazine is a sulfonamide antibiotic.

Contents

Uses

It eliminates bacteria that cause infections by stopping the production of folic acid inside the bacterial cell, and is commonly used to treat urinary tract infections (UTIs).

In combination, sulfadiazine and pyrimethamine, can be used to treat toxoplasmosis, a disease caused by Toxoplasma gondii. This may present in an AIDS patient as multiple ring enhancing lesions on CT. Pregnant women should avoid contact with cat litter which may contain Toxoplasma oocysts.

Side effects

Side effects reported for sulfadiazine include: nausea, upset stomach, loss of appetite, and dizziness.

Brand names

Lantrisul; Neotrizine; Sulfa-Triple #2; Sulfadiazine; Sulfaloid; Sulfonamides Duplex; Sulfose; Terfonyl; Triple Sulfa; Triple Sulfas; Triple Sulfoid

See also

External links



 
 

 

Copyrights:

Dictionary. The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2007. Published by Houghton Mifflin Company. All rights reserved.  Read more
Drug Info. Gold Standard. Copyright © 2008 by Gold Standard. All rights reserved.  Read more
Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved.  Read more
Wikipedia. This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Sulfadiazine" Read more