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sulfone

 
Dictionary: sul·fone   (sŭl'fōn') pronunciation
n.
Any of various organic sulfur compounds having a sulfonyl group attached to two carbon atoms, especially such a compound formerly used as a drug to treat leprosy or tuberculosis.


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Medical Dictionary: sul·fone
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(sŭl'fōn')
n.

Any of various organic sulfur compounds having a sulfonyl group attached to two carbon atoms, especially such a compound formerly used as a drug to treat leprosy or tuberculosis.

A compound containing two hydrocarbon radicals attached to the −SO2− group, especially dapsone (4,4′-sulfonylbisbenzenamine) and its derivatives, which are potent antibacterials effective against many gram-positive and gram-negative organisms, and are widely used in humans as leprostatics.

Wikipedia: Sulfone
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The structure of a sulfone.

A sulfone is a chemical compound containing a sulfonyl functional group attached to two carbon atoms. The central sulfur atom is twice double bonded to oxygen and has two further hydrocarbon substituents. The general structural formula is R-S(=O)(=O)-R' where R and R' are the organic groups. The use of the alternative name sulphone is discouraged by IUPAC. Sulfides are often the starting materials for sulfones by organic oxidation through the intermediate formation of sulfoxides. For example dimethyl sulfide is oxidized to dimethyl sulfoxide and then to dimethyl sulfone.

In the Ramberg-Bäcklund Reaction and the Julia olefination sulfones are converted to alkenes.

Examples of sulfones include dapsone, a drug formerly used as an antibiotic to treat leprosy, dermatitis herpetiformis, tuberculosis, or pneumocystis pneumonia (PCP).

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Dictionary. The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2009. Published by Houghton Mifflin Company. All rights reserved.  Read more
Medical Dictionary. The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company Read more
Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved.  Read more
Wikipedia. This article is licensed under the Creative Commons Attribution/Share-Alike License. It uses material from the Wikipedia article "Sulfone" Read more