== == Amyloid beta (AB) protein is produced from the cleavage of amyloid precursor protein (APP: a transmembrane protein) by beta secretase and gamma secretase. The build up of this intact AB protein leads to formation of amyloid plaques. Tau is a group of microtubule associated proteins which contributes to the assembly and stabilization of microtubules in axons. However, hyperphosphorylation of tau leads to tau aggregation and formation of neurofibrillary tangles (NFT). Intracellular NFT and extracellular amyloid plaques are two pathological hallmarks of Alzheimer's disease.

Tau is a protein which may be responcible for alziemers; it tangles nerve cells therefore killing brain cells.

The gene encodes a scaffold protein that maintains the shape of brain neurons by stabilizing cellular microtubules. Mutations to the tau protein cause it to form clumps and limit its ability to assemble microtubules

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Bobby Tau's birth name is Robert Tau.